诊断工具在产琥珀酸厌氧螺菌菌血症识别中的作用
Place of diagnostic tools in the identification of Anaerobiospirillum succiniciproducens bacteraemia.
作者信息
Decroix V, Pluquet E, Choquet M, Ammenouche N, Castelain S, Guiheneuf R
机构信息
Department of Bacteriology, Amiens University Hospital, Amiens, France; Microbiology Research Unit, EA4294, Jules Verne University of Picardie, France.
Department of Bacteriology, Amiens University Hospital, Amiens, France.
出版信息
Anaerobe. 2016 Jun;39:28-30. doi: 10.1016/j.anaerobe.2016.02.005. Epub 2016 Feb 16.
Anaerobiospirillum succiniciproducens is a rare but potentially lethal pathogen. We report a case of A. succiniciproducens bloodstream infection in a 55-year-old man hospitalized for pelvic trauma. The strain was identified by 16sRNA sequencing after several failures of identification by MALDI-TOF MS. The strain was susceptible to beta-lactam antibiotics and ciprofloxacin, but resistant to macrolides and clindamycin. Identification tools must be improved to enhance our knowledge on this rare pathogen and to define optimal therapy.
产琥珀酸厌氧螺菌是一种罕见但可能致命的病原体。我们报告了一例55岁因骨盆创伤住院的男性患者发生产琥珀酸厌氧螺菌血流感染的病例。在基质辅助激光解吸电离飞行时间质谱（MALDI-TOF MS）多次鉴定失败后，通过16sRNA测序鉴定出该菌株。该菌株对β-内酰胺类抗生素和环丙沙星敏感，但对大环内酯类和克林霉素耐药。必须改进鉴定工具，以增进我们对这种罕见病原体的了解并确定最佳治疗方法。
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