Laudereau Jean-Baptiste, Grabar Alexander A, Tanter Mickaël, Gennisson Jean-Luc, Ramaz François
Opt Express. 2016 Feb 22;24(4):3774-89. doi: 10.1364/OE.24.003774.
Due to multiple light scattering inside biological tissues, deep non-invasive optical medical imaging is very challenging. Acousto-optic imaging is a technique coupling ultrasound and light that allows recovering optical contrast at depths of few centimeters with a millimeter resolution. Recent advances in acousto-optic imaging are using short focused ultrasound pulses often averaged over several hundred or thousand pulses. As the pulsing rate of commercial probes is limited to about few ultrasound cycles every 100 μs, acquiring an acousto-optic image usually takes several tens of seconds due to the high number of acoustic pulses excitation. We propose here a new acousto-optic imaging technique based on the use of ultrasound plane waves instead of focused ones that allows increasing drastically the imaging rate.
由于生物组织内部存在多重光散射,深度非侵入式光学医学成像极具挑战性。声光成像是一种将超声与光相结合的技术,能够以毫米级分辨率在几厘米深度处恢复光学对比度。声光成像的最新进展是使用短聚焦超声脉冲,这些脉冲通常在数百或数千个脉冲上进行平均。由于商用探头的脉冲频率限制为每100微秒约几个超声周期,由于需要大量的声脉冲激发,获取一幅声光图像通常需要几十秒。我们在此提出一种基于使用超声平面波而非聚焦波的新型声光成像技术,该技术可大幅提高成像速率。