Moreira Ana Regina Oliveira, Santamaria Mauro Pedrine, Silvério Karina Gonzales, Casati Marcio Zaffalon, Nociti Junior Francisco Humberto, Sculean Anton, Sallum Enilson Antonio
Department of Prosthodontics and Periodontics, Division of Periodontics, Piracicaba Dental School, State University of Campinas - UNICAMP, Av. Limeira, 901, Areião, Piracicaba, São Paulo, Brazil.
Department of Periodontology, São José dos Campos Dental School, State University of São Paulo, São José dos Campos, São Paulo, Brazil.
Clin Oral Investig. 2016 Dec;20(9):2539-2549. doi: 10.1007/s00784-016-1757-8. Epub 2016 Feb 26.
The objective of this study is to clinically evaluate the outcomes following treatment of single gingival recessions with either coronally advanced flap technique (CAF) alone or combined with a porcine collagen matrix graft (CM).
This is a randomized parallel design clinical trial, including forty patients with single Miller Class I or II gingival recession, with a depth ≥ 2 mm and located at upper canines or premolars. The patients were randomly assigned to receive either CAF or CAF + CM. The primary outcome variable was gingival recession reduction (Rec Red).
Baseline recession depth was 3.14 ± 0.51 mm for CAF group and 3.16 ± 0.65 mm for CAF + CM group (p > 0.05). Both groups showed significant Rec Red (p < 0.05), up to 6 months. Rec Red for CAF + CM was 2.41 ± 0.73 mm and was 2.25 ± 0.50 mm for CAF alone (p > 0.05). Root coverage was 77.2 % in the CAF + CM group and 72.1 % in the CAF group (p > 0.05). Complete root coverage (CRC) was found in 40 % of the cases in the CAF + CM group and in 35 % of the sites treated with CAF. Keratinized tissue thickness (KTT) was 0.26 mm higher in CAF + CM group (p < 0.05).
It can be concluded that CAF + CM does not provide a superior recession reduction when compared to CAF; however, it may offer a small gain in KTT after 6 months.
CAF + CM can be suggested as a valid therapeutic option to achieve root coverage and some increase in soft tissue thickness after 6 months.
本研究的目的是临床评估单独使用冠向复位瓣技术(CAF)或联合猪胶原蛋白基质移植物(CM)治疗单发性牙龈退缩后的效果。
这是一项随机平行设计的临床试验,纳入40名单发性米勒I类或II类牙龈退缩患者,退缩深度≥2mm,位于上颌尖牙或前磨牙处。患者被随机分配接受CAF或CAF+CM治疗。主要结局变量是牙龈退缩减少量(Rec Red)。
CAF组基线退缩深度为3.14±0.51mm,CAF+CM组为3.16±0.65mm(p>0.05)。两组在长达6个月时均显示出显著的Rec Red(p<0.05)。CAF+CM组的Rec Red为2.41±0.73mm,单独CAF组为2.25±0.50mm(p>0.05)。CAF+CM组的牙根覆盖率为77.2%,CAF组为72.1%(p>0.05)。CAF+CM组40%的病例实现了完全牙根覆盖(CRC),CAF治疗部位为35%。CAF+CM组的角化组织厚度(KTT)高0.26mm(p<0.05)。
可以得出结论,与CAF相比,CAF+CM在减少牙龈退缩方面并无优势;然而,6个月后它可能在KTT方面有小幅增加。
CAF+CM可作为一种有效的治疗选择,以实现牙根覆盖并在6个月后使软组织厚度有所增加。