Zani Augusto, Pierro Agostino
Division of General and Thoracic Surgery, University of Toronto, The Hospital for Sick Children, Toronto, Canada.
F1000Res. 2015 Nov 30;4. doi: 10.12688/f1000research.6888.1. eCollection 2015.
Necrotizing enterocolitis is a devastating intestinal disease that affects ~5% of preterm neonates. Despite advancements in neonatal care, mortality remains high (30-50%) and controversy still persists with regards to the most appropriate management of neonates with necrotizing enterocolitis. Herein, we review some controversial aspects regarding the epidemiology, imaging, medical and surgical management of necrotizing enterocolitis and we describe new emerging strategies for prevention and treatment.
坏死性小肠结肠炎是一种严重的肠道疾病,影响约5%的早产儿。尽管新生儿护理取得了进展,但死亡率仍然很高(30%-50%),对于坏死性小肠结肠炎新生儿的最佳治疗方法仍存在争议。在此,我们回顾了坏死性小肠结肠炎在流行病学、影像学、内科和外科治疗方面的一些争议点,并描述了新出现的预防和治疗策略。