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钙化冠状动脉病变的治疗。

Treatment of calcified coronary artery lesions.

作者信息

Farag Mohamed, Costopoulos Charis, Gorog Diana A, Prasad Abhiram, Srinivasan Manivannan

机构信息

a Department of Cardiology , East and North Hertfordshire NHS Trust , Hertfordshire , UK.

b Department of Cardiovascular Medicine , University of Cambridge , Cambridge , UK.

出版信息

Expert Rev Cardiovasc Ther. 2016 Jun;14(6):683-90. doi: 10.1586/14779072.2016.1159513. Epub 2016 Mar 15.

Abstract

Heavily calcified coronary plaques represent a complex lesion subset and a challenge to the interventional cardiologist, as they are often resistant to simple plaque modification with conventional balloon angioplasty. Inadequate plaque modification can lead to stent underdeployment, which itself predisposes to in-stent restenosis and stent thrombosis. Over the years, a number of mechanical devices ranging from modified angioplasty balloons to atherectomy devices have become available in order to tackle such lesions. Here we review these devices concentrating on the evidence behind their use.

摘要

严重钙化的冠状动脉斑块代表了一类复杂的病变亚组,对介入心脏病专家来说是一项挑战,因为它们通常对传统球囊血管成形术这种简单的斑块修饰方法具有抵抗性。斑块修饰不充分会导致支架展开不全,而这本身又易引发支架内再狭窄和支架血栓形成。多年来,为了应对这类病变,已经有许多机械设备可供使用,从改良的血管成形术球囊到旋切装置。在此,我们回顾这些设备,重点关注其使用背后的证据。

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