韩国成年人慢性肾脏病患病率的近期趋势：1998年至2013年韩国国民健康与营养检查调查
Recent trends in the prevalence of chronic kidney disease in Korean adults: Korean National Health and Nutrition Examination Survey from 1998 to 2013.
作者信息
Shin Hyun-Young, Kang Hee-Taik
机构信息
Department of Family Medicine, Myongji Hospital, Seonam University, College of Medicine, Goyang-city, Gyeonggi-do, Republic of Korea.
Department of Epidemiology and Health Promotion, Institute for Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Republic of Korea.
出版信息
J Nephrol. 2016 Dec;29(6):799-807. doi: 10.1007/s40620-016-0280-y. Epub 2016 Mar 4.
BACKGROUND
Chronic kidney disease (CKD) is associated with aging, diabetes, hypertension, dyslipidemia, obesity, and unhealthy lifestyle behaviors and has become a public health burden worldwide.
METHODS
We investigated the trends of CKD prevalence over a period of 16 years in Korean adults based on the Korean National Health and Nutrition Examination Survey (KNHANES): phase I (1998), II (2001), III (2005), IV (2007-09), V (2010-2012), and VI (2013). Of the 105,504 individuals aged over 20 years who participated in KNHANES I-VI, 55,191 (23,729 men and 31,462 women) were included in the present study.
RESULTS
The sequential percentage of glomerular filtration rate (GFR) <60 ml/min/1.73 m in KNHANES I-VI was 1.0, 4.2, 3.2, 1.9, 1.6, and 2.1 % in men and 3.6, 9.3, 10.4, 3.1, 1.6, and 2.0 % in women, respectively. The percentage of proteinuria ≥1+ in men rebounded after KNHANES V (3.1, 2.9, 2.8, 1.9, 1.1, and 1.7 % in KNHANES I-VI, respectively), but in women declined across all KNHANES reads (3.4, 2.3, 1.4, 1.6, 1.0, and 0.9 %, respectively). The prevalence of CKD rebounded after KNHANES V for men (3.9, 6.8, 5.5, 3.5, 2.4, and 3.5 % in KNHANES I-VI) while those in women decreased to a plateau level (6.6, 10.9, 11.4, 4.2, 2.4, and 2.4 % in KNHANES I-VI, respectively).
CONCLUSIONS
Our study shows that the prevalence of CKD in Korean adults has decreased overall, but since KNHANES V there has been a rebound in men while no changes in women.
背景
慢性肾脏病（CKD）与衰老、糖尿病、高血压、血脂异常、肥胖及不健康的生活方式行为相关，已成为全球公共卫生负担。
方法
我们基于韩国国家健康与营养检查调查（KNHANES）调查了16年间韩国成年人CKD患病率的趋势：第一阶段（1998年）、第二阶段（2001年）、第三阶段（2005年）、第四阶段（2007 - 2009年）、第五阶段（2010 - 2012年）和第六阶段（2013年）。在参与KNHANES I - VI的105,504名20岁以上个体中，本研究纳入了55,191名（23,729名男性和31,462名女性）。
结果
在KNHANES I - VI中，男性肾小球滤过率（GFR）<60 ml/min/1.73 m²的连续百分比分别为1.0%、4.2%、3.2%、1.9%、1.6%和2.1%，女性分别为3.6%、9.3%、10.4%、3.1%、1.6%和2.0%。男性蛋白尿≥1+的百分比在KNHANES V之后有所反弹（在KNHANES I - VI中分别为3.1%、2.9%、2.8%、1.9%、1.1%和1.7%），但女性在所有KNHANES调查中均下降（分别为3.4%、2.3%、1.4%、1.6%、1.0%和0.9%）。男性CKD患病率在KNHANES V之后有所反弹（在KNHANES I - VI中分别为3.9%、6.8%、5.5%、3.5%、2.4%和3.5%），而女性则降至平稳水平（在KNHANES I - VI中分别为6.6%、10.9%、11.4%、4.2%、2.4%和2.4%）。
结论
我们的研究表明，韩国成年人CKD患病率总体呈下降趋势，但自KNHANES V以来男性患病率出现反弹，而女性患病率无变化。
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