Osti Leonardo, Buda Matteo, Buono Angelo Del, Osti Raffaella, Massari Leo
Unit of Arthroscopy and Sports Medicine, Hesperia Hospital, Modena, Italy.
Department of Orthopaedic and Traumatology, University of Ferrara, Italy.
Muscles Ligaments Tendons J. 2016 Feb 13;5(4):270-5. doi: 10.11138/mltj/2015.5.4.270. eCollection 2015 Oct-Dec.
the aim of this quantitative review is to document potential benefit and adverse effects of hyaluronic acid (HA) injection into the shoulder with rotator cuff tears.
a systematic literature search was performed in english PubMed, Medline, Ovid, Google Scholar and Embase databases using the combined key words "hyaluronic acid", "rotator cuff tear", "hyaluronate", "shoulder", "viscosupplementation", with no limit regarding the year of publication. Articles were included if they reported data on clinical and functional outcomes, complications in series of patients who had undergone HA injection for management of rotator cuff tears. Two Authors screened the selected articles for title, abstract and full text in accordance with predefined inclusion and exclusion criteria. The papers were accurately analyzed focusing on objective rating scores reported.
a total of 11 studies, prospective, 7 were randomized were included by full text. A total of 1102 patients were evaluated clinically after different HA injection compare with corticosteroid injection, physically therapies, saline solution injection and control groups. The use of HA in patients with rotator cuff tears improve VAS and functional score in all trials that we have analyzed.
intra-articular injection with HA is effective in reducing pain and improving function in shoulder with rotator cuff tears and without severe adverse reaction.
Level I.
本定量综述旨在记录透明质酸(HA)注射治疗肩袖撕裂的潜在益处和不良反应。
在英文的PubMed、Medline、Ovid、谷歌学术和Embase数据库中进行系统的文献检索,使用组合关键词“透明质酸”、“肩袖撕裂”、“透明质酸盐”、“肩部”、“粘弹性补充疗法”,对发表年份无限制。如果文章报告了接受HA注射治疗肩袖撕裂的一系列患者的临床和功能结局、并发症的数据,则纳入研究。两名作者根据预先定义的纳入和排除标准,对所选文章的标题、摘要和全文进行筛选。重点分析文章中报告的客观评分,对这些论文进行准确分析。
共纳入11项前瞻性研究,其中7项为随机研究。与皮质类固醇注射、物理治疗、生理盐水注射和对照组相比,共有1102例患者在接受不同的HA注射后进行了临床评估。在我们分析的所有试验中,HA用于肩袖撕裂患者均改善了视觉模拟评分(VAS)和功能评分。
关节内注射HA可有效减轻肩袖撕裂患者肩部疼痛并改善功能,且无严重不良反应。
I级。