Cas9对脱靶位点的结合变得松弛。 - Suppr

Cas9 loosens its grip on off-target sites.

作者信息

Nelson Christopher E, Gersbach Charles A

机构信息

Department of Biomedical Engineering, and at the Center for Genomic &Computational Biology, Duke University, Durham, North Carolina, USA.

出版信息

Nat Biotechnol. 2016 Mar;34(3):298-9. doi: 10.1038/nbt.3501.

DOI:10.1038/nbt.3501

PMID:26963555

Abstract

摘要

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相似文献

Cas9 loosens its grip on off-target sites.

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Mol Cell. 2015 Nov 5;60(3):398-407. doi: 10.1016/j.molcel.2015.10.030.

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引用本文的文献

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Int J Mol Sci. 2022 Oct 1;23(19):11669. doi: 10.3390/ijms231911669.

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The evolving EU regulatory framework for precision breeding.

Theor Appl Genet. 2019 Mar;132(3):569-573. doi: 10.1007/s00122-018-3200-9. Epub 2018 Oct 17.

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Genome Biol. 2018 Aug 15;19(1):107. doi: 10.1186/s13059-018-1482-5.

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Bioengineered. 2016 Apr;7(3):166-74. doi: 10.1080/21655979.2016.1189039.

本文引用的文献

Editing the epigenome: technologies for programmable transcription and epigenetic modulation.

Nat Methods. 2016 Feb;13(2):127-37. doi: 10.1038/nmeth.3733.

Genome-editing Technologies for Gene and Cell Therapy.

Mol Ther. 2016 Mar;24(3):430-46. doi: 10.1038/mt.2016.10. Epub 2016 Jan 12.

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Nature. 2016 Jan 28;529(7587):490-5. doi: 10.1038/nature16526. Epub 2016 Jan 6.

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Nature. 2015 Apr 9;520(7546):186-91. doi: 10.1038/nature14299. Epub 2015 Apr 1.

Genome editing. The new frontier of genome engineering with CRISPR-Cas9.

Science. 2014 Nov 28;346(6213):1258096. doi: 10.1126/science.1258096.

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Nature. 2014 Sep 25;513(7519):569-73. doi: 10.1038/nature13579. Epub 2014 Jul 27.

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Nat Biotechnol. 2014 Mar;32(3):279-284. doi: 10.1038/nbt.2808. Epub 2014 Jan 26.

Cas9 loosens its grip on off-target sites.

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