在巴布亚新几内亚农村地区，含米索前列醇的清洁分娩包用于自我给药预防产后出血的可行性及可接受性。

Feasibility and acceptability of clean birth kits containing misoprostol for self-administration to prevent postpartum hemorrhage in rural Papua New Guinea.

作者信息

Vallely Lisa M, Homiehombo Primrose, Walep Elizabeth, Moses Michael, Tom Marynne, Kelly-Hanku Angela, Vallely Andrew, Nataraye Eluo, Ninnes Caroline, Mola Glen D, Morgan Chris, Kaldor John M, Wand Handan, Whittaker Andrea, Homer Caroline S E

机构信息

The Kirby Institute, University of New South Wales, Sydney, NSW, Australia; Sexual and Reproductive Health Unit, Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea.

Sexual and Reproductive Health Unit, Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea.

出版信息

Int J Gynaecol Obstet. 2016 Jun;133(3):301-6. doi: 10.1016/j.ijgo.2015.10.018. Epub 2016 Feb 24.

DOI:10.1016/j.ijgo.2015.10.018

PMID:26971258

Abstract

OBJECTIVE

To determine the feasibility and acceptability of providing clean birth kits (CBKs) containing misoprostol for self-administration in a rural setting in Papua New Guinea.

METHODS

A prospective intervention study was conducted between April 8, 2013, and October 24, 2014. Eligible participants were women in the third trimester of pregnancy who attended a prenatal clinic in Unggai Bena. Participants received individual instruction and were then given a CBK containing 600μg misoprostol tablets for self-administration following an unsupervised birth if they could demonstrate their understanding of correct use of items in the CBK. Data regarding the use and acceptability of the CBK and misoprostol were collected during postpartum follow-up.

RESULTS

Among 200 participants, 106 (53.0%) had an unsupervised birth, and 99 (93.4%) of these women used the CBK. All would use the CBK again and would recommend it to others. Among these 99 women, misoprostol was self-administered by 98 (99.0%), all of whom would take the drug again and would recommend it to others.

CONCLUSION

The findings strengthen the case for community-based use of misoprostol to prevent postpartum hemorrhage in remote communities. Large-scale interventions should be planned to further evaluate impact and acceptability.

摘要

目的

确定在巴布亚新几内亚农村地区提供含米索前列醇的清洁分娩包（CBK）供自我给药的可行性和可接受性。

方法

于2013年4月8日至2014年10月24日进行了一项前瞻性干预研究。符合条件的参与者为在温盖贝纳产前诊所就诊的妊娠晚期妇女。参与者接受了个体指导，然后如果她们能证明理解CBK中物品的正确使用方法，就会得到一个含600μg米索前列醇片的CBK，以便在无监督分娩后自我给药。在产后随访期间收集有关CBK和米索前列醇使用及可接受性的数据。