癌症患者不明原因发热。
Fever of unknown origin in cancer patients.
机构信息
Medicine Department, Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles, Brussels, Belgium.
Medicine Department, Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles, Brussels, Belgium.
出版信息
Crit Rev Oncol Hematol. 2016 May;101:125-30. doi: 10.1016/j.critrevonc.2016.02.015. Epub 2016 Feb 27.
Fever of unknown origin (FUO) remains a challenging clinical problem, namely in patients with cancer. In cancer patients, FUO may be due to the cancer itself, as it is the case of hematological malignancies; digestive tumors (colon cancer, liver metastases) are significantly associated with FUO and infection can be demonstrated in some cases. Prevention with G-CSF and empirical antimicrobial therapy are essential approaches for the management of FUO in cancer patients. New diagnostic approaches, such as PET imaging, should be further evaluated in cancer patients with FUO.
不明原因发热（FUO）仍然是一个具有挑战性的临床问题，尤其是在癌症患者中。在癌症患者中，FUO 可能是由于癌症本身引起的，例如血液系统恶性肿瘤；消化系统肿瘤（结肠癌、肝转移）与 FUO 有显著相关性，某些情况下可证实存在感染。在癌症患者中，使用 G-CSF 和经验性抗菌治疗进行预防是管理 FUO 的重要方法。对于 FUO 的癌症患者，应进一步评估新的诊断方法，如 PET 成像。
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