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艾哈迈德青光眼阀植入前血流测试及术后早期临床结果

Preimplantation Flow Testing of Ahmed Glaucoma Valve and the Early Postoperative Clinical Outcome.

作者信息

Jones Emma, Alaghband Pouya, Cheng Jason, Beltran-Agullo Laura, Sheng Lim Kin

机构信息

Consultant, Department of Glaucoma, Accident and Emergency, Moorfields Hospital NHS Trust, London, United Kingdom.

Glaucoma Research Fellow, Department of Ophthalmology, St Thomas' Hospital, London, United Kingdom.

出版信息

J Curr Glaucoma Pract. 2013 Jan-Apr;7(1):1-5. doi: 10.5005/jp-journals-10008-1128. Epub 2013 Jan 15.

Abstract

PURPOSE

The Ahmed glaucoma valve (AGV) implant is designed to prevent early postoperative hypotony. There is evidence of variation in hypotony rates in clinical trials which may be due to surgical technique variation, entry site leakage or valve defects from 'over priming'. We describe a simple preimplantation gravity driven test to assess valve function after priming that may reduce hypotony rates.

MATERIALS AND METHODS

Retrospective case note review. An in vivo flow test of AGVs, based on the gravity driven test was introduced prior to implantation. The onset and offset of flow through the valve was measured by altering the height of a bottle of balanced saline solution. We rejected the AGV, if there was fluid still flowing at 10 cm (7 mm Hg) or if there was no flow at 17 cm of water (12 mm Hg). The AGV implantation surgery was without mitomycin C, with a 25G needle entry tract, a corneal or scleral patch graft tube cover and without intracameral viscoelastic.

RESULTS

Twenty Ahmed valves were implanted in 16 patients between July 2008 and October 2009. Test failure resulted in four AGV being rejected. The mean preoperative pressure was 29 mm Hg (range, 10-57 mm Hg) and the intraocular pressure (IOP) at 7 days postoperatively was 15 mm Hg (range, 3-52 mm Hg). Hypotony, defined as an IOP of less than 5 mm Hg on two consecutive assessments, was present in two eyes (10%).

CONCLUSION

In vivo flow testing is an important safety check for the AGV. There are also other mechanisms after implantation that can cause an unexpected high or low IOP. How to cite this article: Jones E, Alaghband P, Cheng J, Beltran-Agullo L, Lim KS. Preimplantation Flow Testing of Ahmed Glaucoma Valve and the Early Postoperative Clinical Outcome. J Current Glau Prac 2013;7(1):1-5.

摘要

目的

艾哈迈德青光眼引流阀(AGV)植入物旨在预防术后早期低眼压。临床试验中有证据表明低眼压发生率存在差异,这可能是由于手术技术差异、穿刺部位渗漏或“过度充盈”导致的瓣膜缺陷。我们描述了一种简单的植入前重力驱动测试,以评估充盈后瓣膜功能,这可能会降低低眼压发生率。

材料与方法

回顾性病例记录审查。在植入前引入了基于重力驱动测试的AGV体内流量测试。通过改变一瓶平衡盐溶液的高度来测量通过瓣膜的血流开始和停止情况。如果在10厘米(7毫米汞柱)时仍有液体流动,或者在17厘米水柱(12毫米汞柱)时没有流动,我们就拒绝使用该AGV。AGV植入手术未使用丝裂霉素C,采用25G针头穿刺路径,角膜或巩膜补片移植管覆盖,且前房未使用粘弹剂。

结果

2008年7月至2009年10月期间,16例患者植入了20个艾哈迈德引流阀。测试失败导致4个AGV被拒收。术前平均眼压为29毫米汞柱(范围为10 - 57毫米汞柱),术后7天眼压为15毫米汞柱(范围为3 - 52毫米汞柱)。定义为连续两次测量眼压低于5毫米汞柱的低眼压在2只眼中出现(10%)。

结论

体内流量测试是AGV的一项重要安全检查。植入后还有其他机制可导致意外的高眼压或低眼压。如何引用本文:琼斯E,阿拉格班德P,程J,贝尔特兰 - 阿古洛L,林KS。艾哈迈德青光眼引流阀植入前流量测试及术后早期临床结果。《当代青光眼实践杂志》2013;7(1):1 - 5。

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