[金昌队列中肺癌的疾病负担]

[Disease burden of lung cancer in Jinchang cohort].

作者信息

Zheng Shan, Pu Hongquan, Dai Min, Bai Yana, Li Haiyan, Chang Sheng, Wang Minzhen, Wang Zhengfang, Zhu Jinbing, Ren Xiaowei, Li Juansheng, Cheng Ning

机构信息

Institute of Epidemiology and Biostatistics, School of Public Health, Center for Cancer Prevention and Control, Lanzhou University, Lanzhou 730000, China.

Workers'Hospital of Jinchuan Group Company Limited, Jinchang 737100, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2016 Mar;37(3):311-5. doi: 10.3760/cma.j.issn.0254-6450.2016.03.003.

DOI:10.3760/cma.j.issn.0254-6450.2016.03.003

PMID:27005526

Abstract

OBJECTIVE

To understand the current status of lung cancer disease burden in Jinchang cohort.

METHODS

In this historical cohort study, the mortality data of the lung cancer from 2001 to 2013 and medical records of the lung cancer cases from 2001 to 2010 in Jinchang cohort were used, analyze mortality, direct economic burden, potential years of life lost (PYLL) and working PYLL (WPYLL) associated with lung cancer.

RESULTS

A total of 434 lung cancer deaths occurred in Jinchang cohort from 2001 to 2013. The crude mortality rate of lung cancer was 78.06 per 100,000 from 2001 to 2013, with the increasing rate of 4.77%. The mortality rate of lung cancer in males and females were about 108.90 per 100,000 and 26.08 per 100,000 with the increasing rate of 4.24% and 6.91%, respectively. During the thirteen years, the PYLL and average PYLL (APYLL) of lung cancer were 3 721.71 person-years and 8.58 years. The APYLL of lung cancer in females (15.94 years) was higher than that in males (7.87 years). The WPYLL and the average WPYLL (AWPYLL) of lung cancer were 1161.00 person-years and 2.68 years, respectively. The AWPYLL of lung cancer was also higher in females than in males. The direct economic burden of lung cancer from 2001 to 2010 in Jinchang cohort was 6309.39 Yuan per case with no increased trend.

CONCLUSION

Lung cancer is the main health problem in Jinchang cohort, causing heavy disease burden.

摘要

目的

了解金昌队列中肺癌疾病负担的现状。

方法

在这项历史性队列研究中，使用了金昌队列2001年至2013年肺癌的死亡率数据以及2001年至2010年肺癌病例的医疗记录，分析与肺癌相关的死亡率、直接经济负担、潜在寿命损失年数（PYLL）和工作寿命损失年数（WPYLL）。

结果

2001年至2013年，金昌队列共发生434例肺癌死亡。2001年至2013年肺癌粗死亡率为每10万人78.06例，增长率为4.77%。男性和女性肺癌死亡率分别约为每10万人108.90例和26.08例，增长率分别为4.24%和6.91%。在这13年中，肺癌的PYLL和平均PYLL（APYLL）分别为3721.71人年和8.58年。女性肺癌的APYLL（15.94年）高于男性（7.87年）。肺癌的WPYLL和平均WPYLL（AWPYLL）分别为1161.00人年和2.68年。肺癌的AWPYLL也是女性高于男性。2001年至2010年金昌队列中肺癌的直接经济负担为每例6309.39元，无上升趋势。