阿尔茨海默病的潜伏期以及tau蛋白与淀粉样蛋白在大脑中错误折叠和扩散的时间。 - Suppr

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The incubation period of Alzheimer's disease and the timing of tau versus amyloid misfolding and spreading within the brain.

作者信息

Goudsmit Jaap

机构信息

Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands.

Janssen Prevention Center, Leiden, The Netherlands.

出版信息

Eur J Epidemiol. 2016 Feb;31(2):99-105. doi: 10.1007/s10654-016-0144-8. Epub 2016 Mar 26.

DOI:10.1007/s10654-016-0144-8

PMID:27017509

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4819914/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d729/4819914/ef0333e2c741/10654_2016_144_Fig1_HTML.jpg

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The incubation period of Alzheimer's disease and the timing of tau versus amyloid misfolding and spreading within the brain.

作者信息

Goudsmit Jaap

机构信息

Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands.

Janssen Prevention Center, Leiden, The Netherlands.

出版信息

Eur J Epidemiol. 2016 Feb;31(2):99-105. doi: 10.1007/s10654-016-0144-8. Epub 2016 Mar 26.

DOI:10.1007/s10654-016-0144-8

PMID:27017509

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4819914/

Abstract

摘要

相似文献

The incubation period of Alzheimer's disease and the timing of tau versus amyloid misfolding and spreading within the brain.

Eur J Epidemiol. 2016 Feb;31(2):99-105. doi: 10.1007/s10654-016-0144-8. Epub 2016 Mar 26.

The molecular pathology of Alzheimer's disease.

Neuroimaging Clin N Am. 2012 Feb;22(1):11-22, vii. doi: 10.1016/j.nic.2011.11.003.

Protein aggregation in Alzheimer's disease: Aβ and τ and their potential roles in the pathogenesis of AD.

Acta Neuropathol. 2015 Feb;129(2):163-5. doi: 10.1007/s00401-015-1387-2.

Alzheimer's disease-related lesions.

J Alzheimers Dis. 2013;33 Suppl 1:S173-9. doi: 10.3233/JAD-2012-129024.

Individual severity of AD-type lesions, Aß oligomers, and comorbidity in the brain aging.

Adv Exp Med Biol. 2015;822:17. doi: 10.1007/978-3-319-08927-0_4.

Alzheimer's disease: cholesterol a menace?

Brain Res Bull. 2011 Aug 10;86(1-2):1-12. doi: 10.1016/j.brainresbull.2011.06.006. Epub 2011 Jul 1.

Understanding the cause of sporadic Alzheimer's disease.

Expert Rev Neurother. 2014 Jun;14(6):621-30. doi: 10.1586/14737175.2014.915740.

Dynamics of plaque formation in Alzheimer's disease.

Biophys J. 1999 Mar;76(3):1330-4. doi: 10.1016/S0006-3495(99)77295-4.

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Adv Exp Med Biol. 2015;821:11-7. doi: 10.1007/978-3-319-08939-3_6.

Alzheimer's disease: Mental plaque removal.

Nature. 2003 May 22;423(6938):392-3. doi: 10.1038/423392a.

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Association between first-line antidepressant use and risk of dementia in older adults: a retrospective cohort study.

BMC Geriatr. 2023 Dec 8;23(1):825. doi: 10.1186/s12877-023-04475-z.

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An experimental model of Braak's pretangle proposal for the origin of Alzheimer's disease: the role of locus coeruleus in early symptom development.

Alzheimers Res Ther. 2019 Jul 3;11(1):59. doi: 10.1186/s13195-019-0511-2.

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Eur J Epidemiol. 2018 Jul;33(7):613-616. doi: 10.1007/s10654-018-0420-x. Epub 2018 Jun 22.

The Rotterdam Study: 2018 update on objectives, design and main results.

Eur J Epidemiol. 2017 Sep;32(9):807-850. doi: 10.1007/s10654-017-0321-4. Epub 2017 Oct 24.

本文引用的文献

Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer's disease related cognitive functioning.

Aging (Albany NY). 2015 Dec;7(12):1198-211. doi: 10.18632/aging.100864.

The Anti-Amyloid-β Monoclonal Antibody 4G8 Recognizes a Generic Sequence-Independent Epitope Associated with α-Synuclein and Islet Amyloid Polypeptide Amyloid Fibrils.

J Alzheimers Dis. 2016;50(2):517-25. doi: 10.3233/JAD-150696.

The preclinical phase of the pathological process underlying sporadic Alzheimer's disease.

Brain. 2015 Oct;138(Pt 10):2814-33. doi: 10.1093/brain/awv236. Epub 2015 Aug 17.

NEURODEGENERATION. Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein.

Science. 2015 Aug 7;349(6248):1255555. doi: 10.1126/science.1255555.

Quantification of biological aging in young adults.

Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):E4104-10. doi: 10.1073/pnas.1506264112. Epub 2015 Jul 6.

Three dimensions of the amyloid hypothesis: time, space and 'wingmen'.

Nat Neurosci. 2015 Jun;18(6):800-6. doi: 10.1038/nn.4018.

PART is part of Alzheimer disease.

Acta Neuropathol. 2015 May;129(5):749-56. doi: 10.1007/s00401-015-1390-7. Epub 2015 Jan 28.

Acta Neuropathol. 2014 Dec;128(6):755-66. doi: 10.1007/s00401-014-1349-0. Epub 2014 Oct 28.

Herpes simplex virus type 1 and Alzheimer's disease: increasing evidence for a major role of the virus.

Front Aging Neurosci. 2014 Aug 11;6:202. doi: 10.3389/fnagi.2014.00202. eCollection 2014.

Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study.

Alzheimers Dement. 2015 Jun;11(6):600-7.e1. doi: 10.1016/j.jalz.2014.06.008. Epub 2014 Aug 15.