Nithya L, Raj N Arunai Nambi, Rathinamuthu Sasikumar
Department of Radiation Oncology, Dharamshila Hospital and Research Centre, New Delhi, India.
Department of Physics, School of Advanced Sciences, VIT University, Vellore, Tamil Nadu, India.
J Med Phys. 2016 Jan-Mar;41(1):34-7. doi: 10.4103/0971-6203.177285.
Analyzing the characteristics of a low monitor unit (MU) setting is essential, particularly for intensity-modulated techniques. Intensity modulation can be achieved through intensity-modulated radiotherapy (IMRT) or volumetric-modulated arc therapy (VMAT). There is possibility for low MUs in the segments of IMRT and VMAT plans. The minimum MU/segment must be set by the physicist in the treatment planning system at the time of commissioning. In this study, the characteristics such as dose linearity, stability, flatness, and symmetry of 6 MV photon beam of a Synergy linear accelerator at low MU settings were investigated for different dose rates. The measurements were performed for Synergy linear accelerator using a slab phantom with a FC65-G chamber and Profiler 2. The MU linearity was studied for 1-100 MU using a field size of 10 cm ×10 cm. The linearity error for 1 MU was 4.2%. Flatness of the beam was deteriorated in 1 MU condition. The beam stability and symmetry was well within the specification. Using this study, we conclude that the treatment delivered with <3 MU may result in uncertainty in dose delivery. To ensure the correct dose delivery with less uncertainty, it is recommended to use ≥3 MU as the minimum MU per segment in IMRT and VMAT plans.
分析低监测单元(MU)设置的特性至关重要,尤其是对于调强技术而言。调强可通过调强放射治疗(IMRT)或容积调强弧形治疗(VMAT)实现。在IMRT和VMAT计划的射野分段中存在低MU的可能性。在调试时,物理学家必须在治疗计划系统中设置每个射野分段的最小MU。在本研究中,针对不同剂量率,研究了Synergy直线加速器在低MU设置下6 MV光子束的剂量线性、稳定性、平坦度和对称性等特性。使用带有FC65 - G电离室的平板模体和Profiler 2对Synergy直线加速器进行测量。使用10 cm×10 cm的射野尺寸,研究了1 - 100 MU的MU线性。1 MU时的线性误差为4.2%。在1 MU条件下,射野的平坦度变差。射野稳定性和对称性完全在规格范围内。通过本研究,我们得出结论,使用<3 MU进行治疗可能会导致剂量传递的不确定性。为确保以较低不确定性正确传递剂量,建议在IMRT和VMAT计划中使用≥3 MU作为每个射野分段的最小MU。