Bacalbasa Nicolae, Taras Cornelia, Orban Carmen, Iliescu Laura, Hurjui Ioan, Hurjui Marcela, Niculescu Nicoleta, Cristea Mirela, Balescu Irina
Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Ilfov County Hospital, Bucharest, Romania.
Anticancer Res. 2016 Apr;36(4):1835-40.
Ovarian leiomyosarcomas are extremely rare ovarian malignancies, usually associated with poor prognosis in terms of survival. Most often, ovarian leiomyosarcomas are diagnosed in postmenopausal women at an advanced stage of disease, the main symptoms consisting of abdominal pain. We present the case of a 52-year-old patient who was initially submitted to surgery for a large ruptured ovarian tumor in April 2009; at that time, total hysterectomy with bilateral adnexectomy, omentectomy, pelvic and para-aortic lymph node dissection were performed. The histopathological studies revealed the presence of an ovarian leiomyosarcoma. Five years later, the patient was diagnosed with a unique, ruptured liver metastasis and an atypical right hepatectomy was performed. The histopathological studies confirmed the metastatic origin of the lesion. At 2-year-follow-up the patient is still free from recurrent disease.
卵巢平滑肌肉瘤是极其罕见的卵巢恶性肿瘤,就生存率而言通常预后较差。卵巢平滑肌肉瘤最常于绝经后女性疾病晚期被诊断出来,主要症状为腹痛。我们报告一例52岁患者的病例,该患者于2009年4月因一个巨大的破裂卵巢肿瘤首次接受手术;当时进行了全子宫切除术、双侧附件切除术、大网膜切除术、盆腔及腹主动脉旁淋巴结清扫术。组织病理学研究显示存在卵巢平滑肌肉瘤。五年后,该患者被诊断出有一个单发的、破裂的肝转移瘤,并接受了非典型性右肝切除术。组织病理学研究证实了该病变的转移起源。在两年的随访中,患者仍无疾病复发。