Ludwig Cancer Research at University of Lausanne, 1066 Epalinges, Switzerland.
The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA.
Sci Transl Med. 2016 Apr 13;8(334):334ps9. doi: 10.1126/scitranslmed.aaf0685.
Cancer vaccine development has been vigorously pursued for 40 years. Immunity to tumor antigens can be elicited by most vaccines tested, but their clinical efficacy remains modest. We argue that a concerted international effort is necessary to understand the human antitumor immune response and achieve clinically effective cancer vaccines.
癌症疫苗的研发已经大力推进了 40 年。大多数已测试的疫苗都能引发针对肿瘤抗原的免疫，但它们的临床疗效仍不显著。我们认为，有必要开展国际间的协同努力，以了解人类抗肿瘤免疫反应并实现临床有效的癌症疫苗。
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