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Low-Level Laser and Light-Emitting Diode Therapy for Pain Control in Hyperglycemic and Normoglycemic Patients Who Underwent Coronary Bypass Surgery with Internal Mammary Artery Grafts: A Randomized, Double-Blind Study with Follow-Up.

作者信息

Lima Andréa Conceição Gomes, Fernandes Gilderlene Alves, Gonzaga Isabel Clarisse, de Barros Araújo Raimundo, de Oliveira Rauirys Alencar, Nicolau Renata Amadei

机构信息

1 Lasertherapy and Photobiology Center, Research and Development Institute , IP&D Universidade do Vale do Paraíba, UNIVAP, São Paulo, Brazil .

2 University of Piauí State (UESPI) , Center of Health Sciences, Teresina, Piauí, Brazil .

出版信息

Photomed Laser Surg. 2016 Jun;34(6):244-51. doi: 10.1089/pho.2015.4049. Epub 2016 Apr 15.

Abstract

OBJECTIVE

This study aimed to evaluate the efficacy of low-level laser therapy (LLLT) and light-emitting diodes (LEDs) for reducing pain in hyperglycemic and normoglycemic patients who underwent coronary artery bypass surgery with internal mammary artery grafts.

METHODS

This study was conducted on 120 volunteers who underwent elective coronary artery bypass graft (CABG) surgery. The volunteers were randomly allocated to four different groups of equal size (n = 30): control, placebo, LLLT [λ = 640 nm and spatial average energy fluence (SAEF) = 1.06 J/cm(2)], and LED (λ = 660 ± 20 nm and SAEF = 0.24 J/cm(2)). Participants were also divided into hyperglycemic and normoglycemic subgroups, according to their fasting blood glucose test result before surgery. The outcome assessed was pain during coughing by a visual analog scale (VAS) and the McGill Pain Questionnaire.

RESULTS

The patients were followed for 1 month after the surgery. The LLLT and LED groups showed a greater decrease in pain, with similar results, as indicated by both the VAS and the McGill questionnaire (p ≤ 0.05), on the 6th and 8th postoperative day compared with the placebo and control groups. The outcomes were also similar between hyperglycemic and normoglycemic patients. One month after the surgery, almost no individual reported pain during coughing.

CONCLUSIONS

LLLT and LED had similar analgesic effects in hyperglycemic and normoglycemic patients, better than placebo and control groups.

摘要

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