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食虫芋螺Conus fulgetrum毒液的特性分析。

Characterization of the venom of the vermivorous cone snail Conus fulgetrum.

作者信息

Abdel-Wahab Mohammed, Miyashita Masahiro, Kitanaka Atsushi, Juichi Hironori, Sarhan Moustafa, Fouda Maged, Abdel-Rahman Mohamed, Saber Samy, Nakagawa Yoshiaki

机构信息

a Zoology Department , Al Azhar University , Assuit , Egypt.

b Graduate School of Agriculture , Kyoto University , Kyoto , Japan.

出版信息

Biosci Biotechnol Biochem. 2016 Oct;80(10):1879-82. doi: 10.1080/09168451.2016.1176519. Epub 2016 Apr 20.

Abstract

Over 200 components with molecular mass ranging mainly from 400 to 4000 Da were characterized from the venom of the vermivorous cone snail Conus fulgetrum that inhabit Egyptian Red Sea. One major component having a molecular mass of 2946 Da was purified by HPLC, and its primary structure was determined by a combination of Edman degradation and MS/MS analysis.

摘要

从栖息于埃及红海的食虫芋螺Conus fulgetrum的毒液中鉴定出200多种主要分子量在400至4000道尔顿之间的成分。通过高效液相色谱法纯化出一种分子量为2946道尔顿的主要成分,并结合埃德曼降解法和串联质谱分析确定了其一级结构。

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