Aung Tin Htun, Judith Beck Adèle, Siese Thomas, Berrisford Richard
Derriford Hospital, Plymouth hospitals NHS trust, UK.
BMJ Qual Improv Rep. 2016 Mar 28;5(1). doi: 10.1136/bmjquality.u207857.w4260. eCollection 2016.
Potentially inappropriate prescribing in healthcare of the elderly (HCE) is associated with avoidable adverse drug events (ADEs).1(,)2 A recent set of prescribing criteria has been designed and validated, called "Screening Tool of Older Persons' Prescriptions" (STOPP), to rationalise prescribing in hospitalised patients on HCE wards.1(,)3 The aim of this quality improvement project was to identify how many potentially inappropriate medications (PIMs) were prescribed on these wards, and remove them. This was executed by implementing a ward round checklist, which incorporated STOPP criteria, for the twice weekly, consultant led ward rounds. This quality improvement project was carried out over four months. In a pilot study, we identified eight inappropriate medical prescriptions among 148 medications (5.4% ) prescribed on one ward. After applying a checklist for a structured ward round, we reviewed the medications prescribed on that ward, and found 10 PIMs out of 192 (5.2% ). Utilising the increasingly recognised "plan, do, study, act" (PDSA) cycle,4 we implemented departmental teaching and meetings with other members of the multidisciplinary team, which raised awareness of PIMs among junior doctors, as well as involving our pharmacists in drug chart screening. During this process we continued with a further six cycles on a bi-weekly basis, and saw a gradual decrease in PIM to 1.5%. In conclusion, a structured ward round, facilitated by a checklist that included review of drug charts based on STOPP criteria, demonstrated a considerable reduction of PIMs. It would be interesting to apply this quality improvement project to non-HCE wards, including general surgical wards or adult psychiatry wards, as a means of not only reducing the effects of ADEs, but also the expenditure associated with unnecessary drug prescriptions, and the costs associated with additional care arising from associated ADEs.
老年人医疗保健中的潜在不适当用药与可避免的药物不良事件(ADEs)相关。最近设计并验证了一套名为“老年人处方筛查工具”(STOPP)的处方标准,以规范老年病科住院患者的用药。本质量改进项目的目的是确定这些科室开具了多少潜在不适当药物(PIMs),并予以停用。这是通过实施一份病房查房清单来实现的,该清单纳入了STOPP标准,用于每周两次由顾问主持的病房查房。这个质量改进项目持续了四个月。在一项试点研究中,我们在一个病房开具的148种药物中发现了8种不适当的医嘱(5.4%)。应用结构化病房查房清单后,我们对该病房开具的药物进行了复查,在192种药物中发现了10种PIMs(5.2%)。利用日益得到认可的“计划、执行、研究、行动”(PDSA)循环,我们开展了科室教学,并与多学科团队的其他成员进行了会议,这提高了初级医生对PIMs的认识,还让我们的药剂师参与药物图表筛查。在此过程中,我们每两周继续进行另外六个循环,PIMs逐渐降至1.5%。总之,由一份基于STOPP标准审查药物图表的清单促成的结构化病房查房,显示PIMs有显著减少。将这个质量改进项目应用于非老年病科病房,包括普通外科病房或成人精神科病房,不仅可以减少ADEs的影响,还可以减少不必要药物处方的费用以及相关ADEs导致的额外护理费用,这将是很有意义的。