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关于磨牙切牙矿化不全与龋齿之间关联的系统评价。

A systematic review on the association between molar incisor hypomineralization and dental caries.

作者信息

Americano Gabriela Caldeira Andrade, Jacobsen Pernille Endrup, Soviero Vera Mendes, Haubek Dorte

机构信息

Innovation Department, Rio de Janeiro State University, Rio de Janeiro, Brazil.

Department of Dentistry, Health, Aarhus University, Aarhus, Denmark.

出版信息

Int J Paediatr Dent. 2017 Jan;27(1):11-21. doi: 10.1111/ipd.12233. Epub 2016 Apr 21.

Abstract

BACKGROUND

Molar incisor hypomineralization (MIH) is a defect of enamel. The lower strength of the enamel can lead to fractures that predispose for plaque accumulation and caries.

AIM

This systematic review aimed to assess the association between MIH and caries.

DESIGN

Studies involving children of all ages, which reported results on MIH and caries in the permanent dentition, were considered eligible. A search was performed in PubMed and was limited to the period from January 2003 to November 2015, and to studies written in English. Reviews, meta-analyses, and case reports were excluded. The studies were evaluated by use of the Newcastle-Ottawa Quality Assessment Scale (NOS).

RESULTS

Seventeen publications were compiled in the review. Most publications reported that children with MIH have higher caries experience. One study did not observe a difference in DMF values among children affected or not by MIH. Three studies reported that children with MIH were 2.1 to 4.6 times more likely to have caries in the permanent dentition than children without MIH.

CONCLUSIONS

A significant association between MIH and caries was found. The results should, however, be interpreted cautiously due to the lack of high-quality studies. The present systematic review confirms the need for further well-designed studies.

摘要

背景

磨牙切牙釉质矿化不全(MIH)是一种牙釉质缺陷。牙釉质强度较低会导致牙齿折断,进而易引发菌斑堆积和龋齿。

目的

本系统评价旨在评估MIH与龋齿之间的关联。

设计

纳入所有年龄段儿童的研究,这些研究报告了恒牙列中MIH和龋齿的结果,则被视为合格。在PubMed上进行检索,检索时间限制为2003年1月至2015年11月,且仅限于英文撰写的研究。排除综述、荟萃分析和病例报告。采用纽卡斯尔-渥太华质量评估量表(NOS)对研究进行评估。

结果

该综述纳入了17篇文献。大多数文献报道,患有MIH的儿童有更高的龋齿患病经历。一项研究未观察到患或未患MIH的儿童之间的龋失补(DMF)值有差异。三项研究报告称,患有MIH的儿童恒牙列患龋的可能性是未患MIH儿童的2.1至4.6倍。

结论

发现MIH与龋齿之间存在显著关联。然而,由于缺乏高质量研究,对结果的解释应谨慎。本系统评价证实需要进一步开展设计良好的研究。

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