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颈神经根病:1420例连续病例的发病率及治疗

Cervical Radiculopathy: Incidence and Treatment of 1,420 Consecutive Cases.

作者信息

Kim Han Jo, Nemani Venu M, Piyaskulkaew Chaiwat, Vargas Samuel Romero, Riew K Daniel

机构信息

Spine Service, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, USA.

Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, MO, USA.

出版信息

Asian Spine J. 2016 Apr;10(2):231-7. doi: 10.4184/asj.2016.10.2.231. Epub 2016 Apr 15.

Abstract

STUDY DESIGN

Retrospective case series.

PURPOSE

To determine the incidence of cervical radiculopathy requiring operative intervention by level and to report on the methods of treatment.

OVERVIEW OF LITERATURE

Cervical radiculopathy is a common cause of pain and can result in progressive neurological deficits. Although the pathology is well understood, the actual incidence of cervical radiculopathy at particular spinal levels ultimately requiring operative intervention is unknown.

METHODS

A large consecutive series of patients operated on by a single surgeon were retrospectively analyzed. The incidence of cervical radiculopathy at each level was defined for every patient. Procedures used for operative treatment were noted. Health related quality of life (HRQL) scores were collected both pre-operatively and postoperatively.

RESULTS

There were 1305 primary and 115 revision operations performed. The most common primary procedures performed were anterior cervical discectomy and fusion (ACDF, 50%) and anterior cervical corpectomy and fusion (ACCF, 28%). The most commonly affected levels were C6 (66%) and C7 (62%). Reasons for revision were pseudarthrosis (27%), clinical adjacent segment pathology (CASP, 63%), persistent radiculopathy (11%), and hardware-related (2.6%). The most common procedures performed in the revision group were posterior cervical decompression and fusion (PCDF, 42%) and ACDF (40%). The most commonly affected levels were C7 (43%) and C5 (30%). Among patients that had their index surgery at our institution, the revision rate was 6.4%. In both primary and revision cases there was a significant improvement in Neck Disability Index and visual analogue scale scores postoperatively. Postoperative HRQL scores in the revision cases were significantly worse than those in the primary cases (p <0.01).

CONCLUSIONS

This study provides the largest description of the incidence of cervical radiculopathy by level and operative outcomes in patients undergoing cervical decompression. The incidence of CASP was 4.2% in 3.3 years in this single institution series.

摘要

研究设计

回顾性病例系列研究。

目的

确定需要手术干预的不同节段颈椎神经根病的发病率,并报告治疗方法。

文献综述

颈椎神经根病是疼痛的常见原因,可导致进行性神经功能缺损。尽管其病理机制已为人熟知,但最终需要手术干预的特定脊柱节段颈椎神经根病的实际发病率尚不清楚。

方法

对由单一外科医生连续进行手术的大量患者进行回顾性分析。为每位患者确定每个节段颈椎神经根病的发病率。记录用于手术治疗的方法。术前和术后收集健康相关生活质量(HRQL)评分。

结果

共进行了1305例初次手术和115例翻修手术。最常见的初次手术是颈椎前路椎间盘切除融合术(ACDF,50%)和颈椎前路椎体次全切除融合术(ACCF,28%)。最常受累的节段是C6(66%)和C7(62%)。翻修的原因包括假关节形成(27%)、临床相邻节段病变(CASP,63%)、持续性神经根病(11%)和与内固定相关(2.6%)。翻修组最常见的手术是颈椎后路减压融合术(PCDF,42%)和ACDF(40%)。最常受累的节段是C7(43%)和C5(30%)。在本院接受初次手术的患者中,翻修率为6.4%。在初次手术和翻修手术病例中,术后颈部功能障碍指数和视觉模拟量表评分均有显著改善。翻修病例的术后HRQL评分明显低于初次手术病例(p<0.01)。

结论

本研究对接受颈椎减压手术患者的不同节段颈椎神经根病发病率及手术结果进行了最大规模的描述。在这个单机构系列研究中,3.3年内CASP的发病率为4.2%。

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