Lancet. 2016 Apr 2;387(10026):1377-1396. doi: 10.1016/S0140-6736(16)30054-X.
Underweight and severe and morbid obesity are associated with highly elevated risks of adverse health outcomes. We estimated trends in mean body-mass index (BMI), which characterises its population distribution, and in the prevalences of a complete set of BMI categories for adults in all countries.
We analysed, with use of a consistent protocol, population-based studies that had measured height and weight in adults aged 18 years and older. We applied a Bayesian hierarchical model to these data to estimate trends from 1975 to 2014 in mean BMI and in the prevalences of BMI categories (<18·5 kg/m(2) [underweight], 18·5 kg/m(2) to <20 kg/m(2), 20 kg/m(2) to <25 kg/m(2), 25 kg/m(2) to <30 kg/m(2), 30 kg/m(2) to <35 kg/m(2), 35 kg/m(2) to <40 kg/m(2), ≥40 kg/m(2) [morbid obesity]), by sex in 200 countries and territories, organised in 21 regions. We calculated the posterior probability of meeting the target of halting by 2025 the rise in obesity at its 2010 levels, if post-2000 trends continue.
We used 1698 population-based data sources, with more than 19·2 million adult participants (9·9 million men and 9·3 million women) in 186 of 200 countries for which estimates were made. Global age-standardised mean BMI increased from 21·7 kg/m(2) (95% credible interval 21·3-22·1) in 1975 to 24·2 kg/m(2) (24·0-24·4) in 2014 in men, and from 22·1 kg/m(2) (21·7-22·5) in 1975 to 24·4 kg/m(2) (24·2-24·6) in 2014 in women. Regional mean BMIs in 2014 for men ranged from 21·4 kg/m(2) in central Africa and south Asia to 29·2 kg/m(2) (28·6-29·8) in Polynesia and Micronesia; for women the range was from 21·8 kg/m(2) (21·4-22·3) in south Asia to 32·2 kg/m(2) (31·5-32·8) in Polynesia and Micronesia. Over these four decades, age-standardised global prevalence of underweight decreased from 13·8% (10·5-17·4) to 8·8% (7·4-10·3) in men and from 14·6% (11·6-17·9) to 9·7% (8·3-11·1) in women. South Asia had the highest prevalence of underweight in 2014, 23·4% (17·8-29·2) in men and 24·0% (18·9-29·3) in women. Age-standardised prevalence of obesity increased from 3·2% (2·4-4·1) in 1975 to 10·8% (9·7-12·0) in 2014 in men, and from 6·4% (5·1-7·8) to 14·9% (13·6-16·1) in women. 2·3% (2·0-2·7) of the world's men and 5·0% (4·4-5·6) of women were severely obese (ie, have BMI ≥35 kg/m(2)). Globally, prevalence of morbid obesity was 0·64% (0·46-0·86) in men and 1·6% (1·3-1·9) in women.
If post-2000 trends continue, the probability of meeting the global obesity target is virtually zero. Rather, if these trends continue, by 2025, global obesity prevalence will reach 18% in men and surpass 21% in women; severe obesity will surpass 6% in men and 9% in women. Nonetheless, underweight remains prevalent in the world's poorest regions, especially in south Asia.
Wellcome Trust, Grand Challenges Canada.
体重过轻、重度肥胖及病态肥胖与不良健康结局风险的大幅升高相关。我们估算了成人平均体重指数(BMI)的变化趋势(BMI可反映其人群分布特征)以及所有国家成人完整BMI类别患病率的变化趋势。
我们采用一致方案分析了针对18岁及以上成年人测量身高和体重的基于人群的研究。我们对这些数据应用贝叶斯分层模型,以估算1975年至2014年200个国家和地区(分为21个区域)按性别划分的平均BMI以及BMI类别(<18.5 kg/m²[体重过轻]、18.5 kg/m²至<20 kg/m²、20 kg/m²至<25 kg/m²、25 kg/m²至<30 kg/m²、30 kg/m²至<35 kg/m²、35 kg/m²至<40 kg/m²、≥40 kg/m²[病态肥胖])的患病率趋势。我们计算了若2000年后的趋势持续,到2025年肥胖率停止上升至2010年水平这一目标实现的后验概率。
我们使用了1698个基于人群的数据源,在进行估算的200个国家中的186个国家有超过1920万成年参与者(990万男性和930万女性)。全球年龄标准化平均BMI在男性中从1975年的21.7 kg/m²(95%可信区间21.3 - 22.1)增至2014年的24.2 kg/m²(24.0 - 24.4),在女性中从1975年的22.1 kg/m²(21.7 - 22.5)增至2014年的24.4 kg/m²(24.2 - 24.6)。2014年男性的区域平均BMI范围从中非和南亚的21.4 kg/m²到波利尼西亚和密克罗尼西亚的29.2 kg/m²(28.6 - 29.8);女性的范围从南亚的21.8 kg/m²(21.4 - 22.3)到波利尼西亚和密克罗尼西亚的32.2 kg/m²(31.5 - 32.8)。在这四十年间,年龄标准化的全球体重过轻患病率在男性中从13.8%(10.5 - 17.4)降至8.8%(7.4 - 10.3),在女性中从14.6%(11.6 - 17.9)降至9.7%(8.3 - 11.1)。2014年南亚体重过轻患病率最高,男性为23.4%(17.8 - 29.2),女性为24.0%(18.9 - 29.3)。年龄标准化的肥胖患病率在男性中从1975年的3.2%(2.4 - 4.1)增至2014年的10.8%(9.7 - 12.0),在女性中从6.4%(5.1 - 7.8)增至14.9%(13.6 - 16.1)。全球2.3%(2.0 - 2.7)的男性和5.0%(4.4 - 5.6)的女性为重度肥胖(即BMI≥35 kg/m²)。全球病态肥胖患病率男性为0.64%(0.46 - 0.86),女性为1.6%(1.3 - 1.9)。
若2000年后的趋势持续,实现全球肥胖目标的概率几乎为零。相反,若这些趋势持续,到2025年,全球肥胖患病率在男性中将达到18%,在女性中超过21%;重度肥胖在男性中将超过6%,在女性中超过9%。尽管如此,体重过轻在世界最贫困地区依然普遍,尤其是在南亚。
惠康信托基金会、加拿大重大挑战项目。