Pasternak Amy, Sideridis Georgios, Fragala-Pinkham Maria, Glanzman Allan M, Montes Jacqueline, Dunaway Sally, Salazar Rachel, Quigley Janet, Pandya Shree, O'Riley Susan, Greenwood Jonathan, Chiriboga Claudia, Finkel Richard, Tennekoon Gihan, Martens William B, McDermott Michael P, Fournier Heather Szelag, Madabusi Lavanya, Harrington Timothy, Cruz Rosangel E, LaMarca Nicole M, Videon Nancy M, Vivo Darryl C De, Darras Basil T
Department of Physical Therapy and Occupational Therapy Services, 300 Longwood Avenue, Boston Children's Hospital, Boston, Massachusetts, USA.
Clinical Research Center, Department of Medicine and Division of Developmental Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Muscle Nerve. 2016 Dec;54(6):1097-1107. doi: 10.1002/mus.25164. Epub 2016 Oct 6.
In this study we evaluated the suitability of a caregiver-reported functional measure, the Pediatric Evaluation of Disability Inventory-Computer Adaptive Test (PEDI-CAT), for children and young adults with spinal muscular atrophy (SMA).
PEDI-CAT Mobility and Daily Activities domain item banks were administered to 58 caregivers of children and young adults with SMA. Rasch analysis was used to evaluate test properties across SMA types.
Unidimensional content for each domain was confirmed. The PEDI-CAT was most informative for type III SMA, with ability levels distributed close to 0.0 logits in both domains. It was less informative for types I and II SMA, especially for mobility skills. Item and person abilities were not distributed evenly across all types.
The PEDI-CAT may be used to measure functional performance in SMA, but additional items are needed to identify small changes in function and best represent the abilities of all types of SMA. Muscle Nerve 54: 1097-1107, 2016.
在本研究中,我们评估了一种由照料者报告的功能测量工具——儿童残疾评估量表计算机自适应测试(PEDI-CAT),用于脊髓性肌萎缩症(SMA)儿童和青年的适用性。
对58名SMA儿童和青年的照料者进行了PEDI-CAT移动性和日常活动领域的题库测试。采用拉施分析来评估不同SMA类型的测试特性。
证实了每个领域的单维内容。PEDI-CAT对III型SMA的信息量最大,在两个领域中能力水平分布接近0.0对数单位。对I型和II型SMA的信息量较少,尤其是在移动技能方面。项目和个体能力在所有类型中分布不均。
PEDI-CAT可用于测量SMA中的功能表现,但需要额外的项目来识别功能的微小变化,并最好地代表所有类型SMA的能力。《肌肉与神经》54: 1097 - 1107, 2016年。