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老年创伤患者死亡率的早期预测指标

Early Predictors of Mortality in Geriatric Patients With Trauma.

作者信息

Wilson Matthew S, Konda Sanjit R, Seymour Rachel B, Karunakar Madhav A

机构信息

*Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, NC; and †Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, NY.

出版信息

J Orthop Trauma. 2016 Sep;30(9):e299-304. doi: 10.1097/BOT.0000000000000615.

Abstract

OBJECTIVE

To identify variables that predict mortality in geriatric patients with trauma.

DESIGN

Retrospective review.

SETTING

Level I trauma center.

PATIENTS/PARTICIPANTS: A total of 147 geriatric patients with trauma (age ≥65) with a predicted probability of survival of 10%-75% based on the Trauma Score-Injury Severity Score (TRISS).

MAIN OUTCOME MEASUREMENTS

Patients were divided into 2 cohorts: survivors and nonsurvivors. The following variables available at presentation were analyzed: age, mechanism of injury, temperature, systolic blood pressure, pulse rate, shock index, respiratory rate, Glasgow Coma Scale (GCS) score, base deficit, and hematocrit (HCT). The Injury Severity Score (ISS) and TRISS were calculated for both cohorts.

RESULTS

Of the 147 patients analyzed, 84 (57%) died during the index hospitalization and 63 (43%) survived. The mean age of nonsurvivors was significantly higher than that of survivors (78.6 vs. 76.1 years; P < 0.04). A greater number of nonsurvivors (72.6%) sustained injuries as a result of a low-energy mechanism compared with survivors (54%; P = 0.02). GCS, temperature, and respiratory rate were significantly lower for nonsurvivors, whereas base deficit was higher (P < 0.05). The TRISS was predictive of survival (TRISS 0.27 vs. 0.53, P < 0.001), but the distinguishing capacity of the TRISS to predict mortality was limited (area under the receiver operator curve; 0.67; 95% confidence interval 0.58-0.76; P < 0.0001).

CONCLUSIONS

Older age, lower GCS, and a low-energy mechanism of injury are associated with a higher mortality rate in this at-risk geriatric trauma population. Early identification of predictors of mortality may help care providers more accurately assess injury burden in geriatric patients.

LEVEL OF EVIDENCE

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

摘要

目的

确定老年创伤患者死亡率的预测变量。

设计

回顾性研究。

地点

一级创伤中心。

患者/参与者:共有147例老年创伤患者(年龄≥65岁),根据创伤评分-损伤严重度评分(TRISS)预测生存概率为10%-75%。

主要观察指标

患者分为两个队列:存活者和非存活者。分析入院时可得的以下变量:年龄、损伤机制、体温、收缩压、脉搏率、休克指数、呼吸频率、格拉斯哥昏迷量表(GCS)评分、碱缺失和血细胞比容(HCT)。计算两个队列的损伤严重度评分(ISS)和TRISS。

结果

在分析的147例患者中,84例(57%)在首次住院期间死亡,63例(43%)存活。非存活者的平均年龄显著高于存活者(78.6岁对76.1岁;P<0.04)。与存活者(54%)相比,更多的非存活者(72.6%)因低能量机制受伤(P=0.02)。非存活者的GCS、体温和呼吸频率显著更低,而碱缺失更高(P<0.05)。TRISS可预测生存(TRISS 0.27对0.53,P<0.001),但TRISS预测死亡率的区分能力有限(受试者工作特征曲线下面积;0.67;95%置信区间0.58-0.76;P<0.0001)。

结论

在这个高危老年创伤人群中,高龄、较低的GCS和低能量损伤机制与较高的死亡率相关。早期识别死亡率预测因素可能有助于医护人员更准确地评估老年患者的损伤负担。

证据水平

预后III级。有关证据水平的完整描述,请参阅作者须知。

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