Ghaly Ramsis F, Lissounov Alexei, Candido Kenneth D, Knezevic Nebojsa Nick
Ghaly Neurosurgical Associates, Aurora, IL, USA; Department of Anesthesiology, Advocate Illinois Masonic Medical Center, Chicago, IL, USA; Department of Anesthesiology, JHS Hospital of Cook County, Chicago, IL, USA; Department of Anesthesiology, University of Illinois, Chicago, IL, USA.
Department of Anesthesiology, Advocate Illinois Masonic Medical Center, Chicago, IL, USA.
Surg Neurol Int. 2016 Apr 7;7:33. doi: 10.4103/2152-7806.179855. eCollection 2016.
Spinal cord stimulators (SCSs) are gaining increasing indications and utility in an expanding variety of clinical conditions. Complications and initial expenses have historically prevented the early use of SCS therapy despite ongoing efforts to educate and promote its utilization. At present, there exists no literature evidence of SCS implantation in a chronically anticoagulated patient, and neuromodulation manufacturers are conspicuously silent in providing warnings or recommendations in the face of anticoagulant use chronically. It would appear as through these issues demand scrutiny and industry as well as neuromodulation society advocacy and support in terms of the provision of coherent guidelines on how to proceed.
A 79-year-old male returned to the neurosurgical clinic with persistent low back pain and leg heaviness due to adjacent level degenerative spondylosis and severe thoracic spinal stenosis. The patient had a notable history of multiple comorbidities along with atrial fibrillation requiring chronic anticoagulation. On initial presentation, he was educated with three choice of conservative medical therapy, intrathecal drug delivery system implantation, or additional lumbar decompression laminectomy with instrumented fusion of T10-L3 and a palliative surgical lead SCS implantation.
A 79-year-old male returned to the neurosurgical clinic with persistent low back pain and leg heaviness due to adjacent level degenerative spondylosis and severe thoracic spinal stenosis. The patient had a notable history of multiple comorbidities along with atrial fibrillation requiring chronic anticoagulation. On initial presentation, he was educated with three choice of conservative medical therapy, intrathecal drug delivery system implantation, or additional lumbar decompression laminectomy with instrumented fusion of T10-L3 and a palliative surgical lead SCS implantation.
Our literature search did not reveal any evidence of SCS therapy among patients with chronic anticoagulation. This case illustrated a complicated clinical case scenario wherein a percutaneous SCS implantation would normally be contraindicated due to severe thoracic spinal stenosis and chronic anticoagulation which could lead to possible paralysis or even a lethal consequences associated with the possible formation of a thoracic epidural hematoma.
脊髓刺激器(SCS)在越来越多的临床病症中的应用指征和效用不断增加。尽管一直在努力开展教育和推广其使用,但并发症和初始费用在历史上一直阻碍着SCS治疗的早期应用。目前,尚无文献证据表明在长期接受抗凝治疗的患者中植入SCS,而且在面对长期使用抗凝剂的情况时,神经调节设备制造商明显未提供任何警告或建议。似乎这些问题需要仔细审查,并且行业以及神经调节协会需要在提供关于如何处理的连贯指南方面进行倡导和支持。
一名79岁男性因相邻节段退行性脊椎病和严重的胸椎椎管狭窄,持续存在下腰痛和腿部沉重感,返回神经外科诊所。该患者有多种合并症的显著病史,同时患有心房颤动,需要长期抗凝治疗。初次就诊时,向他介绍了三种选择:保守药物治疗、鞘内药物输送系统植入,或额外的腰椎减压椎板切除术并进行T10-L3的器械融合以及姑息性手术导联SCS植入。
一名79岁男性因相邻节段退行性脊椎病和严重的胸椎椎管狭窄,持续存在下腰痛和腿部沉重感,返回神经外科诊所。该患者有多种合并症的显著病史,同时患有心房颤动,需要长期抗凝治疗。初次就诊时,向他介绍了三种选择:保守药物治疗、鞘内药物输送系统植入,或额外的腰椎减压椎板切除术并进行T10-L3的器械融合以及姑息性手术导联SCS植入。
我们的文献检索未发现长期抗凝患者接受SCS治疗的任何证据。该病例说明了一种复杂的临床情况,其中由于严重的胸椎椎管狭窄和长期抗凝,经皮SCS植入通常是禁忌的,这可能导致可能的瘫痪甚至与可能形成胸椎硬膜外血肿相关的致命后果。