Uggla L, Bonde L O, Svahn B M, Remberger M, Wrangsjö B, Gustafsson B
Astrid Lindgren Children's Hospital, Karolinska University Hospital-Huddinge, Stockholm, Sweden.
Center for Allogeneic Stem Cell Transplantation, Karolinska University Hospital Huddinge, Stockholm, Sweden.
Acta Paediatr. 2016 Oct;105(10):1225-30. doi: 10.1111/apa.13452. Epub 2016 Jun 3.
Paediatric recipients of haematopoietic stem cell transplants (HSCT) are at increased risk of developing post-traumatic stress disorder (PTSD), and there is a need to identify interventions that can alleviate stress in this group. The aim of this study was to examine the previously unexplored effect of music therapy on children undergoing HSCT, by analysing physiological parameters and comparing them with a control group.
We performed a randomised clinical pilot study of 24 patients up to the age of 16 undergoing HSCT at Karolinska University Hospital, Huddinge, Sweden. Music therapy, including expressive and receptive elements, was performed twice a week in the treatment group and compared to standard care in the control group. Physiological parameters were evaluated according to the hospital's protocols.
The music therapy group had significantly reduced evening heart rates compared to the control group (p < 0.001), and the effect was sustainable for four to eight hours after the intervention. There were no significant differences in saturation or blood pressure observed between the groups.
Music therapy significantly lowered the heart rate of children undergoing HSCT for at least four to eight hours, indicating reduced stress levels and potentially lowering the risk of developing PTSD.
造血干细胞移植(HSCT)的儿科接受者患创伤后应激障碍(PTSD)的风险增加,因此需要确定能够减轻该群体压力的干预措施。本研究的目的是通过分析生理参数并与对照组进行比较,来研究音乐疗法对接受HSCT的儿童此前未被探索的影响。
我们在瑞典胡丁厄的卡罗林斯卡大学医院对24名16岁以下接受HSCT的患者进行了一项随机临床试验。治疗组每周进行两次包括表达性和接受性元素的音乐疗法,并与对照组的标准护理进行比较。根据医院的方案评估生理参数。
与对照组相比,音乐治疗组的夜间心率显著降低(p < 0.001),且该效果在干预后可持续四至八小时。两组之间在饱和度或血压方面未观察到显著差异。
音乐疗法显著降低了接受HSCT的儿童的心率至少四至八小时,表明压力水平降低,并有可能降低患PTSD的风险。