Guerra Montero Luis, Ortega Alvarez Félix, Marquez Teves Maguin, Asato Higa Carmen, Sumire Umeres Julia
Unidad de Trasplante de órganos y Tejidos, Hospital Nacional Ramiro Priale Priale. Huancayo, Perú.
Servicio de Anatomía Patológica, Hospital Nacional Guillermo Almenara Irigoyen. Lima, Perú.
Rev Gastroenterol Peru. 2016 Jan-Mar;36(1):77-80.
Autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune cholangitis are chronic autoimmune liver disease, usually present separate, the cases where characteristics of two of the above is observed liver disease is commonly referred to as Overlap Syndromes (OS). Although there is no consensus on specific criteria for the diagnosis of OS identification of this association is important for initiating appropriate treatment and prevent its progression to cirrhosis or at least the complications of cirrhosis and death. We report the case of awoman aged 22 cirrhotic which debuted are edematous ascites, severe asthenia and jaundice compliant diagnostics SS criteria and initially present any response to treatment with ursodeoxycholic acid and oral corticosteroids, but ultimately finished performing a transplant orthotopic liver.
自身免疫性肝炎、原发性胆汁性肝硬化、原发性硬化性胆管炎和自身免疫性胆管炎是慢性自身免疫性肝病,通常单独出现,观察到具有上述两种疾病特征的肝病病例通常称为重叠综合征(OS)。尽管对于OS诊断的具体标准尚无共识,但识别这种关联对于启动适当治疗并防止其进展为肝硬化或至少预防肝硬化并发症和死亡非常重要。我们报告了一名22岁肝硬化女性的病例,该患者最初表现为水肿性腹水、严重乏力和黄疸,符合诊断标准,最初对熊去氧胆酸和口服皮质类固醇治疗无任何反应,但最终接受了原位肝移植。