Urrutia-Aliano Débora, Segura Eddy R
Departamento de Urología, Hospital Militar Central del Perú, Lima, Perú. Address: Calle José Gonzáles 458, Departamento 501, Miraflores, Lima, Perú. Email:
Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas, Lima, Perú
Medwave. 2016 Apr 29;16(3):e6435. doi: 10.5867/medwave.2016.03.6435.
Patients with type 2 diabetes mellitus (DB2) are more prone to poor quality of life, disability and even death. They also have a greater predisposition to depression compared with non-diabetic patients; as well as a favorable prognosis after mental health-oriented interventions.
The aim of this study was to explore the presence of depressive symptoms in an outpatient population diagnosed with DB2 and military affiliation. Also, to examine the factors associated with the presence of depressive symptoms.
We performed a cross sectional study in 108 people with type 2 diabetes mellitus in January 2012 in an outpatient sample of a military hospital. Depressive symptoms were assessed with Zungs self-administered test. We used the chi-square test or Fisher's exact test to examine associations between depressive symptoms and factors of interest. We use crude and adjusted generalized linear models to estimate prevalence ratios (PRs) for association between clinical and sociodemographic characteristics with the presence of depressive symptoms.
The prevalence of depressive symptoms was 56.5% (95% CI: 46.6 to 66.0%). The bivariate analysis showed significant association between depressive symptoms and variables: sex, age and clinical complications of diabetes. Adjusted analysis showed that diabetic retinopathy [RP: 1.3; 95% CI: 1.1-1.7], and diabetic neuropathy [RP: 1.4; 95% CI: 1.1-1.7] were associated with a greater presence of depressive symptoms after taking into account sex of participants.
We observed a high prevalence of depressive symptoms in the study population, especially in female or elderly patients. This was also true among subjects with late complications of type 2 diabetes mellitus that likely represent the impact of the disease on quality of life and its ultimate effect being manifested as depressive symptoms. A multidisciplinary approach focusing on mental health-oriented aspects should be considered, as it could benefit the evolution of these patients in Peru.
2型糖尿病(DB2)患者更容易出现生活质量低下、残疾甚至死亡。与非糖尿病患者相比,他们患抑郁症的倾向也更大;并且在接受以心理健康为导向的干预后预后良好。
本研究的目的是探讨在诊断为DB2且有军事背景的门诊患者中抑郁症状的存在情况。此外,研究与抑郁症状存在相关的因素。
2012年1月,我们在一家军队医院的门诊样本中对108名2型糖尿病患者进行了横断面研究。使用Zung自评量表评估抑郁症状。我们使用卡方检验或Fisher精确检验来检查抑郁症状与感兴趣因素之间的关联。我们使用粗模型和校正后的广义线性模型来估计临床和社会人口学特征与抑郁症状存在之间关联的患病率比(PRs)。
抑郁症状的患病率为56.5%(95%置信区间:46.6至66.0%)。双变量分析显示抑郁症状与以下变量之间存在显著关联:性别、年龄和糖尿病的临床并发症。校正分析显示,在考虑参与者性别后,糖尿病视网膜病变[相对危险度(RP):1.3;95%置信区间:1.1 - 1.7]和糖尿病神经病变[RP:1.4;95%置信区间:1.1 - 1.7]与抑郁症状的更普遍存在相关。
我们在研究人群中观察到抑郁症状的高患病率,尤其是在女性或老年患者中。在2型糖尿病晚期并发症患者中也是如此,这可能代表了疾病对生活质量的影响,其最终影响表现为抑郁症状。应考虑采用以心理健康为导向的多学科方法,因为这可能有利于秘鲁这些患者的病情发展。