Pereira Keith, Halpern Joshua A, McClure Timothy D, Lewis Nicholas A, Kably Isaam, Bhatia Shivank, Hu Jim C
Department of Interventional Radiology, St. Louis University Hospital, St. Louis, MO, USA.
Department of Urology, Weill Cornell Medical College, New York, NY, USA.
BJU Int. 2016 Sep;118(3):359-65. doi: 10.1111/bju.13524. Epub 2016 Jun 13.
Prostatic haematuria is among the most common genitourinary complaints of emergency room visits, distressing and troublesome to men and a challenging clinical problem to the treating physician. The most common aetiologies of prostatic haematuria include benign prostatic hyperplasia and prostate cancer. Prostatic haematuria usually resolves with conservative and medical methods; failure of these interventions results in refractory haematuria of prostatic origin (RHPO), a potentially life-threatening scenario. Several different treatments have been described, with varying degrees of success. Patients with RHPO are often elderly and unfit for radical surgery. Prostate artery embolization (PAE) has evolved as a safe and effective technique in the management of RHPO. Use of a superselective approach optimizes clinical success while minimizing complications. This minimally invasive approach improves patients with haemodynamic instability, serves as a bridge to elective surgery, and is a highly effective treatment for RHPO. It may obviate the need for more invasive and morbid surgical therapies. The aim of the present review was to describe the current management of RHPO and the technique of PAE and to review its efficacy and associated morbidity.
前列腺血尿是急诊室就诊时最常见的泌尿生殖系统疾病之一,给男性带来痛苦和困扰,对治疗医生来说也是一个具有挑战性的临床问题。前列腺血尿最常见的病因包括良性前列腺增生和前列腺癌。前列腺血尿通常通过保守治疗和药物治疗得以缓解;这些干预措施失败会导致前列腺源性难治性血尿(RHPO),这是一种潜在的危及生命的情况。已经描述了几种不同的治疗方法,其成功率各不相同。RHPO患者通常年事已高,不适合进行根治性手术。前列腺动脉栓塞术(PAE)已发展成为一种治疗RHPO的安全有效的技术。采用超选择性方法可优化临床疗效,同时将并发症降至最低。这种微创方法可改善血流动力学不稳定的患者,作为择期手术的桥梁,并且是治疗RHPO的高效方法。它可能无需进行更具侵入性和危害性的手术治疗。本综述的目的是描述RHPO的当前治疗方法和PAE技术,并综述其疗效和相关发病率。