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吡喃黄酮类化合物的植物资源、结构特征、生物活性及合成

The Plant Resources, Structure Characteristics, Biological Activities and Synthesis of Pyranoflavonoids.

作者信息

Yang Bao, Yang Jiali, Zhao Yupeng, Liu Huiling, Jiang Yueming

机构信息

Key Laboratory of Plant Resources Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.

出版信息

Curr Med Chem. 2016;23(27):3078-3115. doi: 10.2174/0929867323666160510123147.

Abstract

Pyranoflavonoids are mainly distributed in Leguminosae, Moraceae. As a potent drug candidate, pyranoflavonoids have attracted much attention in late years due to their impressive pharmaceutical activities. The structure characteristics, plant resources and pharmaceutical activities of pyranoflavonoids are reviewed in this paper. The fragmentation in mass spectrometry is also discussed for quick identification of these chemicals. Due to the low abundance of this flavonoid sub-class in plants, it is required to find an efficient way to synthesize them. Therefore, an overview of chemical synthesis and biological synthesis is presented in this paper. The information given in this paper will be helpful to know pyranoflavonoids and to be utilized in medicines and nutraceuticals.

摘要

吡喃黄酮主要分布于豆科和桑科。作为一种有潜力的候选药物,吡喃黄酮因其令人瞩目的药理活性近年来备受关注。本文综述了吡喃黄酮的结构特征、植物资源和药理活性。还讨论了质谱中的裂解情况以便快速鉴定这些化合物。由于该类黄酮在植物中的含量较低,需要找到一种有效的合成方法。因此,本文对化学合成和生物合成进行了概述。本文提供的信息将有助于了解吡喃黄酮并将其应用于医药和营养保健品中。

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