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人类肠道微生物群及其与饮食的相互联系。

The human gut microbiota and its interactive connections to diet.

作者信息

Milani C, Ferrario C, Turroni F, Duranti S, Mangifesta M, van Sinderen D, Ventura M

机构信息

Laboratory of Probiogenomics, Department of Life Sciences, University of Parma, Parma, Italy.

GenProbio Ltd, Italy.

出版信息

J Hum Nutr Diet. 2016 Oct;29(5):539-46. doi: 10.1111/jhn.12371. Epub 2016 May 10.

Abstract

The microbiota of the gastrointestinal tract plays an important role in human health. In addition to their metabolic interactions with dietary constituents, gut bacteria may also be involved in more complex host interactions, such as modulation of the immune system. Furthermore, the composition of the gut microbiota may be important in reducing the risk of contracting particular gut infections. Changes in the microbiota during an individual's lifespan are accompanied by modifications in multiple health parameters, and such observations have prompted intense scientific efforts aiming to understand the complex interactions between the microbiota and its human host, as well as how this may be influenced by diet.

摘要

胃肠道微生物群在人类健康中起着重要作用。除了与饮食成分的代谢相互作用外,肠道细菌还可能参与更复杂的宿主相互作用,如免疫系统的调节。此外,肠道微生物群的组成在降低感染特定肠道疾病的风险方面可能很重要。个体一生中微生物群的变化伴随着多个健康参数的改变,这些观察结果促使科学界做出巨大努力,旨在了解微生物群与其人类宿主之间的复杂相互作用,以及饮食如何影响这种相互作用。

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