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Homozygosity for a haplotype in the HBG2-OR51B4 region is exclusive to Arab-Indian haplotype sickle cell anemia.

作者信息

Vathipadiekal Vinod, Alsultan Abdulrahman, Baltrusaitis Kristin, Farrell John J, Al-Rubaish Abdullah M, Al-Muhanna Fahad, Naserullah Zaki, Suliman Ahmed, Patra P K, Milton Jacqueline N, Farrer Lindsay A, Chui David H K, Al-Ali Amein K, Sebastiani Paola, Steinberg Martin H

机构信息

Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.

Sickle Cell Disease Research Center and Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

Am J Hematol. 2016 Jun;91(6):E308-11. doi: 10.1002/ajh.24368. Epub 2016 Apr 28.

Abstract
摘要

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本文引用的文献

2
BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia.
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3
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Nat Rev Mol Cell Biol. 2015 Mar;16(3):167-77. doi: 10.1038/nrm3953. Epub 2015 Feb 18.
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Structural basis of transcription initiation by RNA polymerase II.
Nat Rev Mol Cell Biol. 2015 Mar;16(3):129-43. doi: 10.1038/nrm3952. Epub 2015 Feb 18.
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Reactivation of developmentally silenced globin genes by forced chromatin looping.
Cell. 2014 Aug 14;158(4):849-860. doi: 10.1016/j.cell.2014.05.050.
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Sickle cell disease in Saudi Arabia: the phenotype in adults with the Arab-Indian haplotype is not benign.
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10
Fetal hemoglobin in sickle cell anemia: genetic studies of the Arab-Indian haplotype.
Blood Cells Mol Dis. 2013 Jun;51(1):22-6. doi: 10.1016/j.bcmd.2012.12.005. Epub 2013 Mar 7.

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