Melamud Alexander, Topilow James S, Cai Ling, He Xin
Washington National Eye Center, Washington Hospital Center, Washington, DC; The Retina Group of Washington, Fairfax, Virginia.
Georgetown University School of Medicine, Georgetown University Medical Center, Washington, DC.
Am J Ophthalmol. 2016 Aug;168:177-182. doi: 10.1016/j.ajo.2016.05.006. Epub 2016 May 14.
To compare visual outcomes among eyes that underwent pars plana vitrectomy (PPV) in combination with either anterior chamber intraocular lens implantation (ACIOL) or scleral suturing of posterior chamber lens (PCIOL).
Retrospective comparative case series.
All eyes presented with aphakia or luxated or subluxated posterior chamber intraocular lens (IOL) following complicated cataract surgery, trauma, or spontaneous dislocation. Eyes involving visually significant macular pathology, past retinal detachment, follow-up of less than 6 months, and surgeries requiring the removal of an ACIOL were excluded. The main outcomes measured were final best-corrected visual acuity (BCVA) and surgical complication rates.
Fifty-seven eyes met inclusion criteria; median follow-up was 13.2 months. Initial median BCVA for ACIOL patients was logMAR 1.301 (Snellen equivalent 20/400, range 20/20 to light perception); final median BCVA was logMAR 0.477 (Snellen equivalent 20/60, range 20/20 to light perception, P < .001). Initial median BCVA for PCIOL patients was logMAR 1.239 (Snellen equivalent 20/347, range 20/60 to light perception); final median BCVA was logMAR 0.301 (Snellen equivalent 20/40, range 20/20 to hand motions, P < .001). The change in BCVA between the 2 groups over the course of the study was similar (P > .05). More epiretinal membrane (ERM) formations occurred postoperatively in the ACIOL group (P = .011). Other complication rates were similar between both groups.
PPV with secondary IOL placement is safe and effective, resulting in improved visual outcomes regardless of the technique used. Patients undergoing ACIOL placement have a higher incidence of ERM formation.
比较接受玻璃体切割术(PPV)联合前房人工晶状体植入术(ACIOL)或后房型人工晶状体巩膜缝线固定术(PCIOL)的患眼的视力预后。
回顾性比较病例系列研究。
所有患眼均为复杂白内障手术、外伤或自发性脱位后出现无晶状体眼或后房型人工晶状体(IOL)脱位或半脱位。排除涉及有视觉意义的黄斑病变、既往视网膜脱离、随访时间少于6个月以及需要取出ACIOL的手术的患眼。主要测量指标为最终最佳矫正视力(BCVA)和手术并发症发生率。
57只患眼符合纳入标准;中位随访时间为13.2个月。ACIOL组患者的初始中位BCVA为logMAR 1.301(相当于Snellen视力表的20/400,范围为20/20至光感);最终中位BCVA为logMAR 0.477(相当于Snellen视力表的20/60,范围为20/20至光感,P <.001)。PCIOL组患者的初始中位BCVA为logMAR 1.239(相当于Snellen视力表的20/347,范围为20/60至光感);最终中位BCVA为logMAR 0.301(相当于Snellen视力表的20/40,范围为20/20至手动,P <.001)。在研究过程中,两组之间BCVA的变化相似(P>.05)。ACIOL组术后视网膜前膜(ERM)形成更多(P =.011)。两组之间的其他并发症发生率相似。
PPV联合二期IOL植入安全有效,无论采用何种技术,均可改善视力预后。接受ACIOL植入的患者ERM形成的发生率较高。