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针对Fuchs角膜营养不良的Descemet膜内皮角膜移植术中角膜散光的稳定性

Corneal Astigmatism Stability in Descemet Membrane Endothelial Keratoplasty for Fuchs Corneal Dystrophy.

作者信息

Yokogawa Hideaki, Sanchez P James, Mayko Zachary M, Straiko Michael D, Terry Mark A

机构信息

*Cornea Service, Devers Eye Institute, Portland, OR; †Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan; and ‡Lions VisionGift, Portland, OR.

出版信息

Cornea. 2016 Jul;35(7):932-7. doi: 10.1097/ICO.0000000000000882.

Abstract

PURPOSE

To calculate the magnitude and angle of the shift in corneal astigmatism associated with Descemet membrane endothelial keratoplasty (DMEK) surgery to determine the feasibility of concurrent astigmatism correction at the time of DMEK triple procedures.

DESIGN

Retrospective study.

METHODS

Forty-seven eyes that previously underwent the DMEK procedure for Fuchs endothelial corneal dystrophy and that had more than 1.0 diopter (D) of front corneal astigmatism preoperatively were identified. All DMEK surgeries used a clear corneal temporal incision of 3.2 mm. Surgically induced astigmatism (SIA) was evaluated 6 months postsurgery with vector analysis using Scheimpflug image reading.

RESULTS

We did not find a difference between pre- and postoperative magnitude of front astigmatism (P = 0.88; paired t test). The magnitude of the SIA front surface was 0.77 ± 0.63 D (range, 0.10-3.14 D). The centroid vector of the SIA front surface was 0.14 at 89.3°. A hyperopic corneal power shift was noted in both the front surface by 0.26 ± 0.74 D (range, 0.45-3.05 D) (P = 0.018; paired t test) and back surface by 0.56 ± 0.55 D (range, 0.25-2.40 D) (P < 0.01; paired t test).

CONCLUSIONS

DMEK surgery induces minimal amounts of corneal astigmatism that is a with-the-rule shift associated with a temporal clear corneal incision. The stability of these data from preop to postop supports the plausibility of incorporating astigmatism correction with the cautious use of toric intraocular lenses for patients with Fuchs corneal dystrophy and cataract.

摘要

目的

计算与Descemet膜内皮角膜移植术(DMEK)相关的角膜散光移位的大小和角度,以确定在DMEK三联手术时同时矫正散光的可行性。

设计

回顾性研究。

方法

确定47只先前因Fuchs内皮角膜营养不良接受DMEK手术且术前角膜前散光超过1.0屈光度(D)的眼睛。所有DMEK手术均采用3.2mm的颞侧透明角膜切口。术后6个月使用Scheimpflug图像读取通过矢量分析评估手术诱导散光(SIA)。

结果

我们未发现术前和术后角膜前散光大小存在差异(P = 0.88;配对t检验)。SIA前表面的大小为0.77±0.63 D(范围,0.10 - 3.14 D)。SIA前表面的质心矢量在89.3°时为0.14。角膜前表面出现远视性屈光力移位,为0.26±0.74 D(范围,0.45 - 3.05 D)(P = 0.018;配对t检验),角膜后表面为0.56±0.55 D(范围,0.25 - 2.40 D)(P < 0.01;配对t检验)。

结论

DMEK手术引起的角膜散光量极小,是与颞侧透明角膜切口相关的顺规性移位。术前到术后这些数据的稳定性支持了对于Fuchs角膜营养不良和白内障患者谨慎使用散光人工晶状体合并散光矫正的合理性。

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