McConeghy Kevin W, Wing Coady
Providence Veterans Affairs Medical Center, Department of Veterans Affairs, United States.
Indiana University, School of Public and Environmental Affairs, United States.
Vaccine. 2016 Jun 24;34(30):3463-8. doi: 10.1016/j.vaccine.2016.04.076. Epub 2016 May 21.
A series of state-level statute changes have allowed pharmacists to provide influenza vaccinations in community pharmacies. The study aim was to estimate the effects of pharmacy-based immunization statutes changes on per capita influenza vaccine prescriptions, adult vaccination rates, and the utilization of other preventive health services.
A quasi-experimental study that compares vaccination outcomes over time before and after states allowed pharmacy-based immunization. Measures of per capita pharmacy prescriptions for influenza vaccines in each state came from a proprietary pharmacy prescription database. Data on adult vaccination rates and preventive health utilization were studied using multiple waves of the Behavioral Risk Factor Surveillance System (BRFSS). The primary outcomes were changes in per capita influenza vaccine pharmacy prescriptions, adult vaccination rates, and preventive health interventions following changes.
Between 2007 and 2013, the number of influenza vaccinations dispensed in community pharmacies increased from 3.2 to 20.9 million. After one year, adopting pharmacist immunization statutes increased per capita influenza vaccine prescriptions by an absolute difference (AD) of 2.6% (95% CI: 1.1-4.2). Adopting statutes did not lead to a significant absolute increase in adult vaccination rates (AD 0.9%, 95% CI: -0.3, 2.2). There also was no observed difference in adult vaccination rates among adults at high-risk of influenza complications (AD 0.8%, 95% CI: -0.2, 1.8) or among standard demographic subgroups. There also was no observed difference in the receipt of preventive health services, including routine physician office visits (AD -1.9%, 95% CI: -4.9, 1.1).
Pharmacists are providing millions of influenza vaccines as a consequence of immunization statutes, but we do not observe significant differences in adult influenza vaccination rates. The main gains from pharmacy-based immunization may be in providing a more convenient way to obtain an important health service.
一系列州级法规的变更允许药剂师在社区药房提供流感疫苗接种服务。本研究的目的是评估基于药房的免疫法规变更对人均流感疫苗处方、成人接种率以及其他预防性健康服务利用情况的影响。
一项准实验研究,比较各州允许基于药房的免疫接种前后不同时间的接种结果。每个州流感疫苗人均药房处方数据来自一个专有的药房处方数据库。使用多轮行为危险因素监测系统(BRFSS)研究成人接种率和预防性健康服务利用情况的数据。主要结果是法规变更后人均流感疫苗药房处方、成人接种率和预防性健康干预措施的变化。
2007年至2013年间,社区药房分发的流感疫苗接种数量从320万增加到2090万。一年后,采用药剂师免疫法规使人均流感疫苗处方绝对差异(AD)增加了2.6%(95%置信区间:1.1 - 4.2)。采用法规并未导致成人接种率显著绝对增加(AD 0.9%,95%置信区间:-0.3,2.2)。在流感并发症高风险成人中(AD 0.8%,95%置信区间:-0.2,1.8)或在标准人口亚组中,成人接种率也未观察到差异。在接受预防性健康服务方面,包括常规医生门诊就诊,也未观察到差异(AD -1.9%,95%置信区间:-4.9,1.1)。
由于免疫法规,药剂师正在提供数百万剂流感疫苗,但我们未观察到成人流感接种率有显著差异。基于药房的免疫接种的主要好处可能在于提供了一种更方便的方式来获得一项重要的健康服务。