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长期服用草药可能导致肠系膜静脉硬化的右半结肠切除术:一例报告及文献复习

Right hemicolectomy for mesenteric phlebosclerosis potentially caused by long-term use of herbal medicine: A case report and literature review.

作者信息

Hoshino Nobuaki, Hasegawa Suguru, Hida Koya, Kawada Kenji, Sakai Yoshiharu

机构信息

Department of Surgery, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.

Department of Surgery, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.

出版信息

Int J Surg Case Rep. 2016;24:191-4. doi: 10.1016/j.ijscr.2016.05.051. Epub 2016 May 31.

Abstract

INTRODUCTION

Mesenteric phlebosclerosis is a rare ischemic disease affecting the colon. Systemic disease and herbal medicine have been pointed out as possible causes, and the disease is characterized by calcifications involved the mesocolic veins. Patients who do not respond to conservative therapy require surgical treatment. In surgical intervention, an adequate extent of colonic resection is important.

PRESENTATION OF CASE

We present a case of an 87-year-old woman with mesenteric phlebosclerosis who had consumed herbal medicine for 40 years. She suffered from ileus caused by mesenteric phlebosclerosis, and the symptoms did not improve with conservative therapy. Right hemicolectomy was performed since the disease was localized in the right colon. Long-term use of herbal medicine was considered the potential cause of mesenteric phlebosclerosis. The postoperative course was mostly uneventful. The patient stopped using herbal medicine and had no signs of recurrence 2 years after surgery.

DISCUSSION AND CONCLUSION

The greatest concern in surgery for mesenteric phleboscrerosis is to detect the affected area, which should be removed. Characteristic findings in computed tomography and intraoperative findings can help to determine the optimal extent of colonic resection. Mesenteric phlebosclerosis caused by herbal medicines occurs as localized disease in the right colon compared with mesenteric phlebosclerosis caused by other pathogenesis. Limited colonic resection is usually indicated for mesenteric phlebosclerosis caused by herbal medicine.

摘要

引言

肠系膜静脉硬化是一种罕见的影响结肠的缺血性疾病。全身性疾病和草药被指出可能是病因,该疾病的特征是结肠系膜静脉出现钙化。对保守治疗无反应的患者需要手术治疗。在手术干预中,足够范围的结肠切除术很重要。

病例介绍

我们报告一例87岁患有肠系膜静脉硬化的女性病例,她服用草药已有40年。她因肠系膜静脉硬化导致肠梗阻,保守治疗后症状未改善。由于病变局限于右半结肠,故行右半结肠切除术。长期服用草药被认为是肠系膜静脉硬化的潜在病因。术后病程大多平稳。患者术后停用草药,术后2年无复发迹象。

讨论与结论

肠系膜静脉硬化手术中最需要关注的是检测出应切除的病变区域。计算机断层扫描的特征性表现和术中所见有助于确定结肠切除的最佳范围。与其他病因引起的肠系膜静脉硬化相比,草药引起的肠系膜静脉硬化多表现为右半结肠的局限性病变。对于草药引起的肠系膜静脉硬化,通常采用局限性结肠切除术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6889/4906139/4eefb80842c9/gr1.jpg

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