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基因组学与公共卫生?古巴的社区遗传学与个性化医疗挑战。

Genomics as public health? Community genetics and the challenge of personalised medicine in Cuba.

作者信息

Gibbon Sahra

机构信息

a Anthropology Department , University College London , UK.

出版信息

Anthropol Med. 2009 Aug 1;16(2):131-46. doi: 10.1080/13648470902940671.

Abstract

Making use of a comparative perspective on the emergence of 'breast cancer genetics' in the different cultural context of the UK and Cuba, this article examines the tensions between the modern promise of genomics as personalised medicine and a commitment to public health. Focusing primarily on the Cuba context and drawing on ethnographic research as part of a collaborative project working with genetic professionals and publics, the article examines the particular technologies, identities and socialities at stake in an emerging and evolving field of genetic medicine. It highlights how long-standing continuities in the commitment to the equitable provision of public health, particularly as this relates to 'family medicine', are central to understanding the scope and expansion of 'community genetics' interventions, even when at the level of local practice, public health is also now subject to the unequal dynamics of economic necessity through the working out of 'lo informal'. Illuminating the different ways agency, risk, responsibility, citizenship and activism get configured by and between publics and health professionals in Cuba, the article reveals the challenges and opportunities posed by predictive genomic medicine in relation to the dynamic and shifting terrain of public health.

摘要

本文利用英国和古巴不同文化背景下“乳腺癌遗传学”出现的比较视角,审视了基因组学作为个性化医疗的现代前景与公共卫生承诺之间的紧张关系。本文主要聚焦古巴背景,并借鉴人种志研究,这是与遗传专业人员和公众合作项目的一部分,探讨了新兴且不断发展的遗传医学领域中涉及的特定技术、身份和社会关系。文章强调,对公平提供公共卫生服务(特别是与“家庭医学”相关的服务)的长期承诺,对于理解“社区遗传学”干预措施的范围和扩展至关重要,即便在地方实践层面,公共卫生如今也因“非正规经济”的运作而受制于经济需求的不平等动态。文章阐明了古巴公众与卫生专业人员之间以及他们内部如何构建能动性、风险、责任、公民身份和行动主义的不同方式,揭示了预测性基因组医学在公共卫生动态变化领域所带来的挑战和机遇。

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