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[人工晶状体眼儿童黄斑水肿与遮盖性弱视鉴别诊断中脑视觉诱发电位的研究]

[Studies on cerebral visual evoked potentials in the differential diagnosis of macular edema and obscration amblyopia in children with artiphakia].

作者信息

Shpak A A, Zubareva L N

出版信息

Vestn Oftalmol. 1989 Jan-Feb;105(2):44-8.

PMID:2728165
Abstract

The cerebral cortex visual evoked potentials (VEP) to chess pattern reversion have been examined in 41 healthy children (41 eyes) and in 25 children (25 eyes) with artiphakia after traumatic cataract extraction, with macular edemas (ME) in 12 of these and obscuration amblyopia (OA) in 13. Comparison of the amplitude-time parameters of the VEP and of treir relationship with the cell size and the chess pattern contrast has shown a characteristic feature of ME, i. e. an increased peak latency (PL) of the first negative deviation (H1 peak) of the VEP to reversion of the chess pattern with 90% contrast. The mean values of PLHI (M +/- m) have been as follows: 107.1 +/- 3.9 ms in children with ME, 93.1 +/- 2.3 ms in those with OA, and 84.9 +/- 0.8 ms in the controls. An elevation of PLHI over 100ms has been recorded in 9 of the 12 patients with ME and only in 1 child with OA. Involvement of the ganglion cells of the central area of the retina is considered as a possible reason of the detected VEP disorders in ME.

摘要

对41名健康儿童(41只眼)以及25名外伤性白内障摘除术后无晶状体的儿童(25只眼)进行了棋盘格翻转的大脑皮质视觉诱发电位(VEP)检查,其中12名有黄斑水肿(ME),13名有遮盖性弱视(OA)。对VEP的幅度 - 时间参数及其与细胞大小和棋盘格对比度的关系进行比较,显示出ME的一个特征,即对于对比度为90%的棋盘格翻转,VEP第一个负向偏差(H1峰)的峰值潜伏期(PL)增加。PLH1(M±m)的平均值如下:ME患儿为107.1±3.9毫秒,OA患儿为93.1±2.3毫秒,对照组为84.9±0.8毫秒。12名ME患者中有9名记录到PLH1超过100毫秒,而OA患儿中只有1名。视网膜中央区域神经节细胞受累被认为是ME中检测到的VEP异常的可能原因。

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