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侵袭性良性脑膜瘤:来自单一神经外科机构的临床特征、手术策略及结果

Invasive benign meningioma: Clinical characteristics, surgical strategies and outcomes from a single neurosurgical institute.

作者信息

Lin Qingtang, Ling Feng, Xu Geng

机构信息

Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100054, P.R. China.

出版信息

Exp Ther Med. 2016 Jun;11(6):2537-2540. doi: 10.3892/etm.2016.3223. Epub 2016 Apr 4.

Abstract

The aim of the present study was to improve the prognosis for patients with invasive benign meningioma by increasing the precision of pre-operative evaluation and refining the surgical resection strategy. A retrospective review of all the cases of invasive benign meningioma admitted to a single institute from 2005 to 2010 was conducted. The clinical characteristics, magnetic resonance imaging (MRI) findings, refined surgical strategies and outcomes were summarized and analyzed. There were 19 cases of invasive benign meningioma among 254 cases of meningioma. Of the earliest 4 cases, a traditional extra-capsular surgical removal approach was applied, which resulted in permanent neurological deficits for all cases. A modified surgical strategy combining intra- and extra-capsular resection techniques was employed for the subsequent 15 cases, which lead to mild neurological impairment in only 1 case. Pre-operative recognition of this unique sub-type of meningioma maybe facilitated by its typical MRI study findings, and the combination of intra- and extra-capsular resection techniques may be of critical importance in achieving complete tumor removal while maintaining intact neurological functions.

摘要

本研究的目的是通过提高术前评估的准确性和完善手术切除策略,改善侵袭性良性脑膜瘤患者的预后。对2005年至2010年收治于单一机构的所有侵袭性良性脑膜瘤病例进行了回顾性研究。总结并分析了其临床特征、磁共振成像(MRI)表现、完善的手术策略及结果。在254例脑膜瘤病例中有19例侵袭性良性脑膜瘤。最早的4例采用传统的囊外手术切除方法,所有病例均导致永久性神经功能缺损。随后的15例采用了囊内和囊外切除技术相结合的改良手术策略,仅1例出现轻度神经功能损害。这种独特亚型脑膜瘤的典型MRI表现可能有助于术前识别,而囊内和囊外切除技术的结合对于在保持神经功能完整的同时实现肿瘤完全切除可能至关重要。

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