Martinez-Del-Campo Eduardo, Turner Jay D, Rangel-Castilla Leonardo, Soriano-Baron Hector, Kalb Samuel, Theodore Nicholas
Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona.
J Neurosurg Pediatr. 2016 Oct;18(4):452-462. doi: 10.3171/2016.2.PEDS15544. Epub 2016 Jun 10.
OBJECTIVE If left untreated, occipitocervical (OC) instability may lead to serious neurological injury or death. Open internal fixation is often necessary to protect the neurovascular elements. This study reviews the etiologies for pediatric OC instability, analyzes the radiographic criteria for surgical intervention, discusses surgical fixation techniques, and evaluates long-term postoperative outcomes based on a single surgeon's experience. METHODS The charts of all patients < 18 years old who underwent internal OC fixation conducted by the senior author were retrospectively reviewed. Forty consecutive patients were identified for analysis. Patient demographic data, OC junction pathology, radiological diagnostic tools, surgical indications, and outcomes are reported. RESULTS The study population consisted of 20 boys and 20 girls, with a mean age of 7.3 years. Trauma (45% [n = 18]) was the most common cause of instability, followed by congenital etiologies (37.5% [n = 15]). The condyle-C1 interval had a diagnostic sensitivity of 100% for atlantooccipital dislocation. The median number of fixated segments was 5 (occiput-C4). Structural bone grafts were used in all patients. Postsurgical neurological improvement was seen in 88.2% (15/17) of patients with chronic myelopathy and in 25% (1/4) of patients with acute myelopathy. Preoperatively, 42.5% (17/40) of patients were neurologically intact and remained unchanged at last follow-up, 42.5% (17/40) had neurological improvement, 12.5% (5/40) remained unchanged, and 2.5% (1/40) deteriorated. All patients had successful fusion at 1-year follow-up. The complication rate was 7.5% (3/40), including 1 case of vertebral artery injury. CONCLUSIONS Occipitocervical fixation is safe in children and provides immediate immobilization, with excellent survival and arthrodesis rates. Of the radiographic tools evaluated, the condyle-C1 interval was the most predictive of atlantooccipital dislocation.
目的 若不治疗,枕颈(OC)不稳可能导致严重神经损伤或死亡。通常需要进行开放性内固定以保护神经血管结构。本研究基于一位外科医生的经验,回顾小儿OC不稳的病因,分析手术干预的影像学标准,讨论手术固定技术,并评估术后长期疗效。方法 对由资深作者实施OC内固定的所有18岁以下患者的病历进行回顾性分析。确定40例连续患者进行分析。报告患者的人口统计学数据、OC交界区病变、放射学诊断工具、手术指征及结果。结果 研究人群包括20例男孩和20例女孩,平均年龄7.3岁。创伤(45%[n = 18])是不稳最常见的原因,其次是先天性病因(37.5%[n = 15])。髁突-C1间隙对寰枕脱位的诊断敏感性为100%。固定节段的中位数为5个(枕骨-C4)。所有患者均使用结构性骨移植。慢性脊髓病患者术后神经功能改善率为88.2%(15/17),急性脊髓病患者为25%(1/4)。术前,42.5%(17/40)的患者神经功能完整,末次随访时无变化;42.5%(17/40)有神经功能改善;12.5%(5/40)无变化;2.5%(1/40)恶化。所有患者在1年随访时均成功融合。并发症发生率为7.5%(3/40),包括1例椎动脉损伤。结论 枕颈固定在儿童中是安全的,能立即实现固定,生存率和融合率良好。在所评估的放射学工具中,髁突-C1间隙对寰枕脱位的预测性最强。