[Electrophysiological analysis of the phenomenon of "blocked" neuromuscular synapses in patients with myasthenia gravis].

Based on the investigation of 33 distal and 163 proximal muscles in myasthenic patients in which posttetanic and postactivation facilitation was studied and adequate proserin doses injected, the authors have shown the "block" phenomenon to be most pronounced in proximal muscles. The authors offered to use the reversibility coefficient as reflecting the possible restoration of neuromuscular conduction. Evaluation of the "block" and a reversibility coefficient plays major role in assessment of contribution of presynaptic structures to operation of mechanisms dicturbing the neuromuscular conductance in myasthenia.