Ju Lu, Wu Xiaoliang, Xu Dake, Pei Lixia, Ning Houxu, Sun Jianhua
Zhongguo Zhen Jiu. 2016 Feb;36(2):203-6.
The application of placebo acupuncture in randomized controlled trials in the past 10 years (2004-2014) in foreign countries was systematically reviewed to summarize the design of placebo acupuncture; according to category of diseases, advantages and disadvantages were analyzed to explore an ideal placebo acupuncture set. By retrieval in PubMed, EMBASE and OVID databases, the clinical study literature which met the inclusion criteria was searched, and the category of diseases, design of placebo acupuncture and clinical efficacy were analyzed. Totally 29 articles were included. The pain was the leading disease in category of diseases; the most commonly used application of placebo acupuncture design was telescopiform sliding blunt needle, accounting for 45. 16%; the treatment locations were non-acupoints mostly; in the needling depth, approximately 60. 00% selected non-penetrating needling and 26. 67% selected superficial needling; 28 articles indicated that acupuncture and placebo acupuncture had clinical effects, accounting for 96. 55%; 37. 93% of articles indicated acupuncture was superior to placebo acupuncture and 37. 93% of articles indicated acupuncture was not superior to placebo acupuncture. It is concluded that the design of placebo acupuncture should consider multiple factors, including main symptoms, operability, security, blinding and specific effects, and the objective indices should be selected for outcome evaluation.
系统回顾过去10年(2004 - 2014年)国外随机对照试验中安慰针刺法的应用情况,总结安慰针刺法的设计;根据疾病类别分析其优缺点,探寻理想的安慰针刺装置。通过检索PubMed、EMBASE和OVID数据库,搜索符合纳入标准的临床研究文献,并分析疾病类别、安慰针刺法设计及临床疗效。共纳入29篇文章。疾病类别中疼痛类疾病居首位;安慰针刺法设计最常用的是套管式滑动钝针,占45.16%;治疗部位大多为非穴位;进针深度方面,约60.00%选择不入皮针刺,26.67%选择浅刺;28篇文章表明针刺与安慰针刺均有临床效果,占96.55%;37.93%的文章表明针刺优于安慰针刺,37.93%的文章表明针刺不优于安慰针刺。结论是安慰针刺法设计应考虑多种因素,包括主要症状、可操作性、安全性、盲法及特异性效应等,且应选择客观指标进行疗效评价。