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巴西南里奥格兰德州某直辖市苯二氮䓬类药物使用者的依赖性和焦虑状况评估。

Assessment of dependence and anxiety among benzodiazepine users in a provincial municipality in Rio Grande do Sul, Brazil.

作者信息

Schallemberger Janaína Barden, Colet Christiane de Fátima

机构信息

Universidade Regional do Noroeste do Estado do Rio Grande do Sul (UNIJUÍ), Ijuí, RS, Brazil.

Departamento de Ciências da Vida (DCVida), UNIJUÍ, Ijuí, RS, Brazil. This paper was presented as a monograph at the School of Pharmacy at UNIJUÍ, Ijuí, RS, Brazil.

出版信息

Trends Psychiatry Psychother. 2016 Jun 27;0:0. doi: 10.1590/2237-6089-2015-0041.

Abstract

INTRODUCTION

Benzodiazepines are among the most prescribed drugs for anxiety and one of the most used drug classes in the world and have a high potential for addiction. The objective of this study was to assess levels of dependence and anxiety among users of these drugs in the public health system.

METHODS

This was a cross-sectional, descriptive and quantitative study. Benzodiazepine users treated on the public health system were selected. Anxiety levels were assessed with the Hamilton Anxiety Scale and dependency with the Benzodiazepine Dependence Self-Report Questionnaire.

RESULTS

Benzodiazepine use was higher among women and in older age groups. Duration of benzodiazepine use was greater than 1 year for all respondents. The dependence assessment indicated that more than half of users were dependent on taking benzodiazepines and most had a severe degree of anxiety.

CONCLUSION

This study found evidence of prolonged and inappropriate use of benzodiazepines. It is necessary to educate users about the risks of these drugs and to develop strategies to rationalize use of these drugs by working with prescribers and dispensers.

摘要

引言

苯二氮䓬类药物是治疗焦虑症最常用的药物之一,也是世界上使用最广泛的药物类别之一,具有很高的成瘾潜力。本研究的目的是评估公共卫生系统中这些药物使用者的依赖程度和焦虑水平。

方法

这是一项横断面、描述性定量研究。选取在公共卫生系统接受治疗的苯二氮䓬类药物使用者。使用汉密尔顿焦虑量表评估焦虑水平,使用苯二氮䓬类药物依赖自评问卷评估依赖程度。

结果

女性和老年人群中苯二氮䓬类药物的使用更为普遍。所有受访者使用苯二氮䓬类药物的时间均超过1年。依赖程度评估表明,超过一半的使用者对服用苯二氮䓬类药物存在依赖,且大多数人有严重程度的焦虑。

结论

本研究发现了苯二氮䓬类药物长期不当使用的证据。有必要对使用者进行关于这些药物风险的教育,并通过与开处方者和药剂师合作制定策略,使这些药物的使用合理化。

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