双硫仑疗法的现状

CURRENT STATUS OF DISULFIRAM THERAPY.

作者信息

Chakraborty P K, Singh H, Divinakumar K J

机构信息

Ex Consultant (Psychiatry), Command Hospital, (Central Command), Lucknow-226 002.

Graded Specialist (Psychiatry), Command Hospital, (Central Command), Lucknow-226 002.

出版信息

Med J Armed Forces India. 2001 Oct;57(4):320-1. doi: 10.1016/S0377-1237(01)80013-7. Epub 2011 Jul 21.

DOI:10.1016/S0377-1237(01)80013-7

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4924115/

Abstract

The effectiveness of disulfiram is linked to the disulfiram-ethanol reaction in the treatment of Alcohol Dependence Syndrome. However disulfiram therapy is associated with various adverse effects and needs a structured and supervised after care program. Relapse rate is very high once disulfiram therapy is discontinued. Keeping these factors in mind disulfiram therapy is used less often today than previously.

摘要

双硫仑在治疗酒精依赖综合征方面的有效性与双硫仑-乙醇反应有关。然而，双硫仑治疗会带来各种不良反应，且需要一个结构化且受监督的后续护理计划。一旦停止双硫仑治疗，复发率非常高。考虑到这些因素，如今双硫仑治疗的使用频率比以前更低。

相似文献

1

CURRENT STATUS OF DISULFIRAM THERAPY.双硫仑疗法的现状

Med J Armed Forces India. 2001 Oct;57(4):320-1. doi: 10.1016/S0377-1237(01)80013-7. Epub 2011 Jul 21.

2

How to get the best out of antabuse.如何充分利用戒酒硫。

Alcohol Alcohol. 1995 Nov;30(6):775-83.

3

The clinical use of disulfiram (Antabuse): a review.双硫仑（戒酒硫）的临床应用：综述

J Psychoactive Drugs. 1988 Jul-Sep;20(3):243-61. doi: 10.1080/02791072.1988.10472495.

4

Refractive hypotension in a patient with disulfiram-ethanol reaction.双硫仑-乙醇反应患者的屈光性低血压

Am J Med Sci. 2007 Jan;333(1):53-5. doi: 10.1097/00000441-200701000-00007.

5

Supervised disulfiram in relapse prevention in alcohol-dependent patients suffering from comorbid borderline personality disorder--a case series.伴有共病边缘型人格障碍的酒精依赖患者的复发性预防中的监督使用戒酒硫——一项病例系列研究。

Alcohol Alcohol. 2010 Mar-Apr;45(2):146-50. doi: 10.1093/alcalc/agq001. Epub 2010 Jan 27.

6

Current Findings and Mechanisms of Action of Disulfiram in the Treatment of Alcohol Dependence.双硫仑治疗酒精依赖的当前研究结果及作用机制

Pharmacopsychiatry. 2016 Jul;49(4):137-41. doi: 10.1055/s-0042-103592. Epub 2016 Mar 17.

7

Disulfiram (antabuse) contracts in treatment of alcoholism.双硫仑（戒酒硫）在治疗酒精中毒方面有作用。

NIDA Res Monogr. 1995;150:65-91.

8

Disulfiram treatment of patients with both alcohol dependence and other psychiatric disorders: a review.

Alcohol Clin Exp Res. 1992 Feb;16(1):125-30. doi: 10.1111/j.1530-0277.1992.tb00648.x.

9

Patient management in disulfiram implant therapy.

Can J Psychiatry. 1979 Oct;24(6):537-41. doi: 10.1177/070674377902400609.

10

Comparative aspects of disulfiram and its metabolites in the disulfiram-ethanol reaction in the rat.大鼠双硫仑-乙醇反应中双硫仑及其代谢产物的比较研究

Biochem Pharmacol. 1989 Feb 1;38(3):413-21. doi: 10.1016/0006-2952(89)90380-8.

本文引用的文献

1

Safety issues concerning the use of disulfiram in treating alcohol dependence.关于使用双硫仑治疗酒精依赖的安全性问题。

Drug Saf. 1999 May;20(5):427-35. doi: 10.2165/00002018-199920050-00003.

2

Monitoring relapse drinking during disulfiram therapy by assay of urinary 5-hydroxytryptophol.通过检测尿中5-羟色醇监测双硫仑治疗期间的复饮情况。

Alcohol Clin Exp Res. 1998 Feb;22(1):111-4.

3

Psychosis during disulfiram therapy for alcoholism.戒酒硫治疗酒精中毒期间的精神病

J Indian Med Assoc. 1997 Mar;95(3):80-1.

4

[Collateral effects of disulfiram on the central nervous system in alcoholics that have become totally abstemious. Description of 8 cases].[戒酒硫对已完全戒酒的酗酒者中枢神经系统的副作用。8例病例描述]

Ann Ital Med Int. 1996 Oct-Dec;11(4):279-83.

5

[Disulfiram (Esperal) toxicity. Apropos of 3 original cases].[双硫仑（依斯美尔）中毒。关于3例原始病例]

Rev Med Interne. 1995;16(1):67-72. doi: 10.1016/0248-8663(96)80667-9.

6

Disulfiram treatment of patients with both alcohol dependence and other psychiatric disorders: a review.

Alcohol Clin Exp Res. 1992 Feb;16(1):125-30. doi: 10.1111/j.1530-0277.1992.tb00648.x.

7

Techniques to enhance compliance with disulfiram.

Alcohol Clin Exp Res. 1992 Dec;16(6):1035-41. doi: 10.1111/j.1530-0277.1992.tb00695.x.

8

Disulfiram therapy--adverse drug reactions and interactions.双硫仑疗法——药物不良反应及相互作用

Acta Psychiatr Scand Suppl. 1992;369:59-65; discussion 65-6. doi: 10.1111/j.1600-0447.1992.tb03317.x.

9

Long-term Antabuse treatment: tolerance and reasons for withdrawal.

Acta Psychiatr Scand Suppl. 1992;369:47-9. doi: 10.1111/j.1600-0447.1992.tb03315.x.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。