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当代心脏手术中术后心房颤动发生率的增加

Increasing Occurrence of Postoperative Atrial Fibrillation in Contemporary Cardiac Surgery.

作者信息

Khan Jahangir, Khan Niina, Loisa Eetu, Sutinen Jaakko, Laurikka Jari

机构信息

Department of Cardiothoracic Surgery, Heart Hospital, Tampere University Hospital, Tampere, Finland.

Department of Cardiothoracic Surgery, Heart Hospital, Tampere University Hospital, Tampere, Finland.

出版信息

J Cardiothorac Vasc Anesth. 2016 Oct;30(5):1302-7. doi: 10.1053/j.jvca.2016.02.013. Epub 2016 Feb 12.

Abstract

OBJECTIVE

Patients referred for cardiac surgery are increasingly older, with a higher prevalence of significant comorbidities and undergoing more extensive surgery. The aim of the study was to ascertain the incidence and presentation of postoperative atrial fibrillation in contemporary patients.

DESIGN

A prospective single-center study.

SETTING

A tertiary academic center.

PARTICIPANTS

Between January 2013 and December 2014, 1,356 consecutive patients (72% male, median age 68), including urgent and emergency cases, were analyzed. Preoperative paroxysmal atrial fibrillation was present in 163 (12%) and chronic in 156 (12%) patients.

INTERVENTIONS

No interventions.

MEASUREMENTS AND MAIN RESULTS

Of the 1,164 patients without chronic atrial fibrillation and surviving at least 5 days, 599 (51%) developed postoperative atrial fibrillation, 43% after bypass, 55% after single valve, 74% after multiple valve, 66% after combined bypass and valve, and 54% after aortic procedures, p<0.001, respectively. In 29%, the duration of postoperative atrial fibrillation was less than 48 hours and did not recur, whereas in 71% the arrhythmia persisted for at least 48 hours or recurred during hospitalization. Patients with postoperative atrial fibrillation were significantly older, had a higher prevalence of previous atrial fibrillation and hypertension, larger left atrium, and required longer hospitalization with increased rates of reoperations and infectious complications.

CONCLUSIONS

The authors report high, 10% to 20% greater than previously described, occurrence of postoperative atrial fibrillation in contemporary patients undergoing cardiac surgery. Most patients with postoperative atrial fibrillation experienced prolonged duration or recurrence of the arrhythmia. The type of surgery, advanced age, and previous atrial fibrillation were the most important risk factors.

摘要

目的

接受心脏手术的患者年龄越来越大,严重合并症的患病率更高,且接受的手术范围更广。本研究的目的是确定当代患者术后房颤的发生率和表现。

设计

一项前瞻性单中心研究。

地点

一家三级学术中心。

参与者

2013年1月至2014年12月期间,对1356例连续患者(72%为男性,中位年龄68岁)进行了分析,包括急诊和紧急情况患者。术前163例(12%)存在阵发性房颤,156例(12%)为慢性房颤。

干预措施

无干预措施。

测量指标和主要结果

在1164例无慢性房颤且存活至少5天的患者中,599例(51%)发生了术后房颤,搭桥术后发生率为43%,单瓣膜置换术后为55%,多瓣膜置换术后为74%,搭桥联合瓣膜置换术后为66%,主动脉手术后为54%,p<0.001。29%的患者术后房颤持续时间少于48小时且未复发,而71%的患者心律失常持续至少48小时或在住院期间复发。术后房颤患者年龄显著更大,既往房颤和高血压患病率更高,左心房更大,住院时间更长,再次手术率和感染并发症发生率更高。

结论

作者报告,在当代接受心脏手术的患者中,术后房颤的发生率较高,比先前描述的高出10%至20%。大多数术后房颤患者经历了心律失常的持续时间延长或复发。手术类型、高龄和既往房颤是最重要的危险因素。

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