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早期快速进展的肠内营养可促进极低出生体重(VLBW)婴儿的生长。

Early, rapidly progressive enteral nutrition promotes growth of very low birth weight (VLBW) infants.

作者信息

Flidel-Rimon Orna, Raz Moriya, Balla Uri, Hofi Lilach, Juster-Reicher Ada, Shinwell Eric S

机构信息

a Department of Neonatology , Kaplan Medical Center , Rehovot , Israel.

b Medical School, Hebrew University , Jerusalem , Israel.

出版信息

J Matern Fetal Neonatal Med. 2017 May;30(10):1227-1231. doi: 10.1080/14767058.2016.1209651. Epub 2016 Jul 21.

Abstract

AIM

This study describes the effects of a quality improvement program to promote improved postnatal nutrition on the growth of very low birth weight (VLBW) infants.

METHODS

Daily data regarding nutrition and growth were collected from the medical record of VLBW infants born during 1995-2010. The infants were grouped by year of birth in order to compare infants from before, during and after the policy change. Evaluation of growth included age in days at a return to birth weight and the proportion of infants with weight below the 10th percentile at discharge.

RESULTS

The caloric and protein intake improved significantly. The age at a return to birth weight fell (p < 0.01) from 14.6 ± 5 d to 11 ± 8 d after the change. The proportion of infants with a discharge weight below the 10th percentile for corrected age fell (p < 0.01) from 72.1% to 42.1%. Data on enteral feeding showed that increased rate of enteral feeds (EF) was associated with better growth (p < 0.001).

CONCLUSION

Increasing awareness led to increase in caloric and protein intake in VLBW infants. Aggressive EF was associated with more rapid weight gain. However, the provision of protein and calories during the first 2 weeks of life still falls short of the latest European Society of Pediatric Gastroenterology, Hepatology and Nutrition recommendations.

摘要

目的

本研究描述了一项质量改进计划对促进极低出生体重(VLBW)婴儿生长的产后营养改善效果。

方法

收集1995年至2010年出生的VLBW婴儿病历中的每日营养和生长数据。根据出生年份对婴儿进行分组,以便比较政策改变前后的婴儿。生长评估包括恢复出生体重时的日龄以及出院时体重低于第10百分位数的婴儿比例。

结果

热量和蛋白质摄入量显著提高。政策改变后,恢复出生体重的年龄从14.6±5天降至11±8天(p<0.01)。出院体重低于矫正年龄第10百分位数的婴儿比例从72.1%降至42.1%(p<0.01)。肠内喂养数据显示,肠内喂养(EF)速率增加与更好的生长相关(p<0.001)。

结论

意识的提高导致VLBW婴儿热量和蛋白质摄入量增加。积极的EF与体重增加更快相关。然而,在出生后的前两周提供的蛋白质和热量仍未达到欧洲儿科胃肠病学、肝病学和营养学会的最新建议。

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