丙戊酸盐诱发的高血压急症

Valproate Induced Hypertensive Urgency.

作者信息

Sivananthan Mauran, Mohiuddin Sarah

机构信息

Child & Adolescent Psychiatry, University of Michigan, 4250 Plymouth Road, Ann Arbor, MI 48103, USA.

出版信息

Case Rep Psychiatry. 2016;2016:1458548. doi: 10.1155/2016/1458548. Epub 2016 Jun 15.

DOI:10.1155/2016/1458548

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4925980/

Abstract

Valproate is a medication used in the treatment of seizures, bipolar disorder, migraines, and behavioral problems. Here we present a case of an 8-year-old boy who presented with hypertensive urgency after initiation of valproate. Primary treatment of his hypertension was ineffective. Blood pressure stabilization was achieved following discontinuation of valproate. Clinicians should be aware of the risk of developing hypertensive urgency with administration of valproate.

摘要

丙戊酸盐是一种用于治疗癫痫、双相情感障碍、偏头痛和行为问题的药物。在此，我们报告一例8岁男孩在开始使用丙戊酸盐后出现高血压急症的病例。其高血压的初始治疗无效。停用丙戊酸盐后血压得以稳定。临床医生应意识到使用丙戊酸盐会有发生高血压急症的风险。

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本文引用的文献

1

Hypertensive emergencies.

Rev Bras Ter Intensiva. 2008 Sep;20(3):305-12.

2

Drug-induced hypertension: an unappreciated cause of secondary hypertension.

Am J Med. 2012 Jan;125(1):14-22. doi: 10.1016/j.amjmed.2011.05.024.

3

Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy.

CNS Drugs. 2002;16(10):669-94. doi: 10.2165/00023210-200216100-00003.

4

Carbamazepine- induced hypertension.

Neurology. 2002 Jul 23;59(2):275-6. doi: 10.1212/wnl.59.2.275.

5

Increased plasma valproate concentrations when coadministered with guanfacine.

J Child Adolesc Psychopharmacol. 1998;8(2):143-7. doi: 10.1089/cap.1998.8.143.

6

Paradoxical hypertension associated with clozapine.

Am J Psychiatry. 1994 Jan;151(1):148.

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