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心血管磁共振在重度主动脉瓣狭窄评估以及经导管主动脉瓣植入术和外科主动脉瓣置换术后评估中的作用。

The role of cardiovascular magnetic resonance in the assessment of severe aortic stenosis and in post-procedural evaluation following transcatheter aortic valve implantation and surgical aortic valve replacement.

作者信息

Musa Tarique Al, Plein Sven, Greenwood John P

机构信息

Multidisciplinary Cardiovascular Research Centre (MCRC) & Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

出版信息

Quant Imaging Med Surg. 2016 Jun;6(3):259-73. doi: 10.21037/qims.2016.06.05.

Abstract

Degenerative aortic stenosis (AS) is the most common valvular disease in the western world with a prevalence expected to double within the next 50 years. International guidelines advocate the use of cardiovascular magnetic resonance (CMR) as an investigative tool, both to guide diagnosis and to direct optimal treatment. CMR is the reference standard for quantifying both left and right ventricular volumes and mass, which is essential to assess the impact of AS upon global cardiac function. Given the ability to image any structure in any plane, CMR offers many other diagnostic strengths including full visualisation of valvular morphology, direct planimetry of orifice area, the quantification of stenotic jets and in particular, accurate quantification of valvular regurgitation. In addition, CMR permits reliable and accurate measurements of the aortic root and arch which can be fundamental to appropriate patient management. There is a growing evidence base to indicate tissue characterisation using CMR provides prognostic information, both in asymptomatic AS patients and those undergoing intervention. Furthermore, a number of current clinical trials will likely raise the importance of CMR in routine patient management. This article will focus on the incremental value of CMR in the assessment of severe AS and the insights it offers following valve replacement.

摘要

退行性主动脉瓣狭窄(AS)是西方世界最常见的瓣膜疾病,预计在未来50年内患病率将翻倍。国际指南提倡将心血管磁共振成像(CMR)用作一种检查工具,以指导诊断并确定最佳治疗方案。CMR是量化左、右心室容积和质量的参考标准,这对于评估AS对整体心脏功能的影响至关重要。鉴于CMR能够在任何平面成像任何结构,它还具有许多其他诊断优势,包括全面可视化瓣膜形态、直接测量瓣口面积、量化狭窄射流,尤其是准确量化瓣膜反流。此外,CMR能够对主动脉根部和弓部进行可靠且准确的测量,这对患者的恰当管理至关重要。越来越多的证据表明,利用CMR进行组织特征分析可为无症状AS患者和接受干预的患者提供预后信息。此外,目前的一些临床试验可能会提升CMR在常规患者管理中的重要性。本文将重点探讨CMR在评估重度AS中的增量价值以及瓣膜置换术后它所提供的见解。

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