出血性和凝血障碍的中枢神经系统并发症

Central Nervous System Complications of Hemorrhagic and Coagulation Disorders.

作者信息

Filatova Irina, Stratchko Lindsay L, Kanekar Sangam

机构信息

Department of Radiology, Hershey Medical Center, The Pennsylvania State University, 500 University Drive, Hershey, PA 17033, USA.

Department of Radiology, Hershey Medical Center, The Pennsylvania State University, 500 University Drive, Hershey, PA 17033, USA; Department of Neurology, Hershey Medical Center, The Pennsylvania State University, 500 University Drive, Hershey, PA 17033, USA.

出版信息

Hematol Oncol Clin North Am. 2016 Aug;30(4):757-77. doi: 10.1016/j.hoc.2016.03.003. Epub 2016 Jun 6.

DOI:10.1016/j.hoc.2016.03.003

PMID:27443996

Abstract

Hematologic disorders affect the central nervous system in a variety of ways, producing a wide range of neurologic disturbances. Early identification of these complications allows for early intervention and better outcome. Cross-sectional imaging plays an important role in identifying brain abnormalities and helps the clinician in deciding appropriate course of action and treatment. This article discuss in short the basics of hemostasis including the coagulation cascade and the application of basic laboratory tests in evaluation of hematologic function. Imaging features of various neurologic disorders associated with these clotting and bleeding diatheses are discussed in detail with illustrations.

摘要

血液系统疾病以多种方式影响中枢神经系统，产生广泛的神经功能障碍。早期识别这些并发症有助于早期干预并取得更好的治疗效果。横断面成像在识别脑部异常方面发挥着重要作用，并有助于临床医生确定适当的行动方案和治疗方法。本文简要讨论止血的基础知识，包括凝血级联反应以及基础实验室检查在血液学功能评估中的应用。文中还配有插图，详细讨论了与这些凝血和出血性疾病相关的各种神经系统疾病的影像学特征。