MacKillop James, Weafer Jessica, C Gray Joshua, Oshri Assaf, Palmer Abraham, de Wit Harriet
Peter Boris Centre for Addictions Research, McMaster University/St. Joseph's Healthcare Hamilton, Hamilton, ON, L8P 3R2, Canada.
Homewood Research Institute, Homewood Health Centre, Guelph, ON, N1E 4J3, Canada.
Psychopharmacology (Berl). 2016 Sep;233(18):3361-70. doi: 10.1007/s00213-016-4372-0. Epub 2016 Jul 23.
Impulsivity has been strongly linked to addictive behaviors, but can be operationalized in a number of ways that vary considerably in overlap, suggesting multidimensionality.
This study tested the hypothesis that the latent structure among multiple measures of impulsivity would reflect the following three broad categories: impulsive choice, reflecting discounting of delayed rewards; impulsive action, reflecting ability to inhibit a prepotent motor response; and impulsive personality traits, reflecting self-reported attributions of self-regulatory capacity.
The study used a cross-sectional confirmatory factor analysis of multiple impulsivity assessments. Participants were 1252 young adults (62 % female) with low levels of addictive behavior, who were assessed in individual laboratory rooms at the University of Chicago and the University of Georgia. The battery comprised a Delay (replace hyphen with space) Discounting Task, Monetary Choice Questionnaire, Conners' Continuous Performance Test, Go/NoGo Task, Stop Signal Task, Barratt Impulsiveness Scale, and the UPPS-P Impulsive Behavior Scale.
The hypothesized three-factor model provided the best fit to the data, although sensation seeking was excluded from the final model. The three latent factors were largely unrelated to each other and were variably associated with substance use.
These findings support the hypothesis that diverse measures of impulsivity can broadly be organized into three categories that are largely distinct from one another. These findings warrant investigation among individuals with clinical levels of addictive behavior and may be applied to understanding the underlying biological mechanisms of these categories.
冲动性与成瘾行为密切相关,但可以通过多种方式进行操作化定义,这些方式在重叠程度上差异很大,这表明冲动性具有多维度性。
本研究检验了以下假设,即多种冲动性测量指标的潜在结构将反映以下三大类:冲动选择,反映对延迟奖励的折扣;冲动行动,反映抑制优势运动反应的能力;冲动人格特质,反映自我报告的自我调节能力归因。
本研究对多种冲动性评估进行了横断面验证性因素分析。参与者为1252名成瘾行为水平较低的年轻人(62%为女性),他们在芝加哥大学和佐治亚大学的个体实验室房间接受评估。测试组包括一个延迟折扣任务、货币选择问卷、康纳斯连续操作测试、Go/NoGo任务、停止信号任务、巴拉特冲动性量表和UPPS-P冲动行为量表。
尽管最终模型中排除了寻求刺激这一因素,但假设的三因素模型对数据的拟合效果最佳。这三个潜在因素在很大程度上彼此不相关,并且与物质使用存在不同程度的关联。
这些发现支持了以下假设,即多种冲动性测量指标大致可分为三大类,且彼此基本不同。这些发现值得在成瘾行为达到临床水平的个体中进行研究,并可能应用于理解这些类别的潜在生物学机制。